Simon Fraser University
Engaging the World

Course Outlines

Spring 2015 - MBB 222 D100

Molecular Biology and Biochemistry (3)

Class Number: 3940

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 6 – Apr 13, 2015: Mon, Wed, Fri, 11:30 a.m.–12:20 p.m.
    Burnaby

    Jan 6 – Apr 13, 2015: Fri, 11:30 a.m.–12:20 p.m.
    Burnaby

  • Exam Times + Location:

    Apr 16, 2015
    Thu, 3:30–6:30 p.m.
    Burnaby

  • Instructor:

    Eugene Chu

  • Prerequisites:

    or Corequisite CHEM 281.

Description

CALENDAR DESCRIPTION:

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis.

COURSE DETAILS:

TOPICS:

  • Introductory Organic Chemistry
  • Weak chemical interactions
  • Thermodynamics and catalysis
  • Amino acids, polypeptides
  • Protein structure, folding
  • Enzyme catalysis, protein function
  • DNA structure
  • DNA replication
  • DNA repair and mutagenesis
  • Mobile genetic elements
  • Chromosome structure, chromatin
  • Prokaryotic transcription
  • Eukaryotic transcription
  • RNA processing
  • Protein synthesis
  • Recombinant DNA and protein techniques

Grading

  • Problem sets 10%
  • 2 Midterms 40%
  • Final Exam 50%

Materials

REQUIRED READING:

Lehninger, Cox and Nelson, Lehninger Principles  of Biochemistry, 6th edition, 2012.  W.H. Freeman & Company.

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
    http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS