Spring 2015 - MBB 423 D100
Protein Structure and Function (3)
Class Number: 5092
Delivery Method: In Person
Course Times + Location:
Tu 8:30 AM – 10:20 AM
BLU 10011, Burnaby
Th 8:30 AM – 9:20 AM
WMC 3210, Burnaby
Exam Times + Location:
Apr 21, 2015
12:00 PM – 3:00 PM
AQ 5016, Burnaby
Prerequisites:two of MBB 321, 322, 323, 331, with a minimum grade of C.
Recent research in transition state theory; specificity in enzyme catalyzed reactions, the use of recombinant DNA techniques to describe and modify enzyme catalysis, the function of enzymes in organic solvents, and the development of new catalytic activities through monoclonal antibody techniques.
3 lecture hours + 1 tutorial hour / week
Through examination of modern research literature, students will learn to assess primary literature reports of structure data, and to formulate hypotheses and apply structural reasoning in investigations of molecular mechanism
Structural basis of protein function:
- Stability and flexibility
- Enzymatic catalysis
- Integrating multiple functions
- X-ray crystallography
- Electron microscopy
- Spectroscopic techniques
- Quizzes/Clicker 15%
- Midterm Exam I 15%
- Written Assignment 15%
- Midterm Exam II 15%
- Final Exam 40%
- Grading is subject to change depending on enrolment.
MATERIALS + SUPPLIES:
iClicker transmitter required during lectures (available from SFU Bookstore).
This course is not textbook-based. Course readings and research journal articles will be available in Library Reserves.
Department Undergraduate Notes:
- Students are advised to review the plagiarism tutorial found at
- For help with writing, learning and study strategies please contact the Student Learning Commons at
- Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail: email@example.com)
SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS