Spring 2015 - MBB 428 D100
Molecular Mechanisms of Microbial Pathogenesis (3)
Class Number: 3981
Delivery Method: In Person
Course Times + Location:
Tu, Th 10:30 AM – 12:20 PM
AQ 3149, Burnaby
Exam Times + Location:
Apr 19, 2015
3:30 PM – 6:30 PM
EDB 7618, Burnaby
Prerequisites:MBB 322 with a minimum grade of C.
The molecular strategies that bacterial, viral and fungal pathogens use to colonize the human body and cause disease will be studied. Using specific organisms as illustrations, emphasis will be placed on the structural biology of molecular systems such as acquisition and use of virulence factors, adhesion to and invasion of host cells, secretion of toxins and immune escape. Prions, zoonoses and emerging diseases will be included. Students who have taken MBB 420 under the same title cannot take this course for further credit.
We will investigate the molecular strategies that microbes use to colonize the human body and cause disease. We will use specific organisms to illustrate molecular systems such as acquisition and use of virulence factors, adhesion to and invasion of host cells, secretion of toxins and immune escape. An emphasis will be placed on the structural biology of these systems. We will cover selected bacterial and viral pathogens as well as prions. We will also discuss antimicrobial interventions, specifically antibiotics, antivirals and vaccines, and the role of the human microbiome in health and disease.
- Two midterm exams and a non-cumulative final exam 80%
- Assignments 20%
Students who have taken MBB 420 under the same title cannot take this course for further credit.
Department Undergraduate Notes:
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