Simon Fraser University
Engaging the World

Course Outlines

Summer 2016 - MBB 429 D100

RNA-mediated Gene Regulation (3)

Class Number: 2861

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 9 – Aug 8, 2016: Wed, Fri, 2:30–4:20 p.m.
    Burnaby

  • Exam Times + Location:

    Aug 18, 2016
    Thu, 12:00–3:00 p.m.
    Burnaby

  • Prerequisites:

    MBB 331 with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes.

COURSE DETAILS:

Lecture topics will include, but are not limited to:

  1. RNA interference in plants and animals
  2. CRISPR bacterial antiviral defense
  3. Transcriptional and translational regulation - riboswitches, tmRNA, IRES elements, 6S RNA, etc.
  4. Post-transcriptional processing - editing, capping and splicing. Naturally occuring ribozymes.

Grading

  • Short Essays 30%
  • Final Exam 30%
  • Short Quizzes 30%
  • Class Participation 10%

Materials

REQUIRED READING:

None. This course is based on primary literature (journal articles).
Supplementary material will be made available from selected texts or journal articles.

RECOMMENDED READING:

Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000.  University Science Books. 
ISBN: 9780935702491

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
    http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

SFU’s Academic Integrity web site contains information on what is meant by academic dishonesty and where you can find resources to help with your studies.  There is also a section on tutoring.  

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS