Summer 2016 - MBB 429 D100
RNA-mediated Gene Regulation (3)
Class Number: 2861
Delivery Method: In Person
Overview
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Course Times + Location:
May 9 – Aug 8, 2016: Wed, Fri, 2:30–4:20 p.m.
Burnaby -
Exam Times + Location:
Aug 18, 2016
Thu, 12:00–3:00 p.m.
Burnaby
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Instructor:
Peter Unrau
punrau@sfu.ca
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Prerequisites:
MBB 331 with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes.
COURSE DETAILS:
Lecture topics will include, but are not limited to:
- RNA interference in plants and animals
- CRISPR bacterial antiviral defense
- Transcriptional and translational regulation - riboswitches, tmRNA, IRES elements, 6S RNA, etc.
- Post-transcriptional processing - editing, capping and splicing. Naturally occuring ribozymes.
Grading
- Short Essays 30%
- Final Exam 30%
- Short Quizzes 30%
- Class Participation 10%
Materials
REQUIRED READING:
None. This course is based on primary literature (journal articles).
Supplementary material will be made available from selected texts or journal articles.
RECOMMENDED READING:
Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000. University Science Books.
ISBN: 9780935702491
Department Undergraduate Notes:
- Students are advised to review the plagiarism tutorial found at
http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial - For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail: csdo@sfu.ca)
Registrar Notes:
SFU’s Academic Integrity web site contains information on what is meant by academic dishonesty and where you can find resources to help with your studies. There is also a section on tutoring.
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS