Fall 2017 - MBB 402 D100

Developmental Biology of Cell Signalling (3)

Class Number: 7813

Delivery Method: In Person

Overview

  • Course Times + Location:

    We, Fr 8:30 AM – 10:20 AM
    AQ 4130, Burnaby

  • Prerequisites:

    MBB 331 or BISC 302W with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

Aspects of developmental biology in the context of signal transduction pathways. The diverse mechanisms used in cell signalling and how the various approaches to the study of signal transduction in organismal development complement each other will be examined with an emphasis on current literature.

COURSE DETAILS:

In this lecture/seminar course, we will examine select aspects of developmental and cellular biology with a focus on signal transduction. Signaling pathways control a wide range of cellular processes and the characterization of these pathways is having a major impact on cell biology, developmental biology and medicine. In this course, we shall be examining the current literature in this rapidly developing field. We will look at how a combination of biochemistry, cell biology and genetics is being used to investigate the diverse mechanisms used in cell signaling, and examine how the various approaches to studying signal transduction compliment each other.

Specific Topics will include:

  1. Introduction: mechanisms of signal transduction, approaches available for studying signal transduction
  2. Signaling pathways involving small GTPase and trimeric G proteins
  3. Signaling by proteolytic cleavages
  4. Wnt and Hedgehog signaling pathways
  5. Regulation of signaling by Kinases and Phosphatases
  6. Other topics as time permits

Grading

  • Midterm Exam 20%
  • Oral Presentation 25%
  • Class Participation 15%
  • Final Term Paper 40%

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
    http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS