Fall 2024 - MBB 328 D100

Introduction to Microbial Pathogenesis (3)

Class Number: 1514

Delivery Method: In Person

Overview

  • Course Times + Location:

    Sep 4 – Dec 3, 2024: Tue, 2:30–4:20 p.m.
    Burnaby

    Sep 4 – Dec 3, 2024: Thu, 2:30–4:20 p.m.
    Burnaby

  • Prerequisites:

    MBB 231 with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections - antibiotics, antiviral agents and vaccines - will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.

COURSE DETAILS:

Description:

We will examine the molecular mechanisms by which microbial pathogens colonize the human body and cause disease. Emphasis will be placed on selected microbes and their structure/morphology, genetics, virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections, including antibiotics, antiviral agents and vaccines, will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.

Course Details:

Host immune response
Overview of virus structure

Selected viral pathogens:

- Polio virus

- Coronaviruses including SARS-CoV2
- Influenza virus

- Human immunodeficiency virus (HIV)

- Human papilloma virus (HPV)

- Herpes simplex virus (HSV)

Antiviral agents and resistance mechanisms

Selected bacterial pathogens:

- Listeria monocytogenes

- Streptococci, Enterococci, Staphylococcus aureus

- Pseudomonas aeruginosa

- pathogenic E. coli

- Klebsiella pneumoniae

Antibiotics and resistance mechanisms
Selected fungal pathogen & parasite

Vaccines
Human microbiota

Grading

  • Two midterm exams and a cumulative final exam 80%
  • Assignments 20%

NOTES:

 



Materials

REQUIRED READING:

Wilson, A.B. (2023). Introduction to Microbial Pathogenesis for Simon Fraser University ePDF.
ISBN: 9781394230235

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html

RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.