Fall 2024 - MBB 445 D100

Infectious Disease Mechanisms (3)

Class Number: 6261

Delivery Method: In Person


  • Course Times + Location:

    Sep 4 – Dec 3, 2024: Tue, Thu, 12:30–2:20 p.m.

  • Prerequisites:

    MBB 328 and either MBB 326 or HSCI 326, all with a minimum grade of C.



Recent advances in microbial pathogenesis with an emphasis on primary literature.


Course Description:
An examination of viruses and bacteria that cause human infections, of antimicrobial agents and resistance as well as vaccines. Each week will cover a different topic in viral or bacterial pathogenesis. A 1-1.5 hr lecture will be delivered on the topic and then students will present results from current literature for discussion. The course will have two sections, (1) Viruses and (2) Bacteria. At the end of each section students will write an exam. They will also present a project in the form of a poster or video on one section or the other.

Schedule (subject to changes):
Week 1: General introduction
Week 2: Overview of viral pathogens
Week 3: Viral life cycle
Week 4: Virus genetics and evolution
Week 5: Host/virus interactions
Week 6: Antiviral agents and vaccines
Week 7: Virus posters
Week 8: Overview of bacterial pathogens
Week 9: Bacterial entry/invasion of host cells
Week 10: Bacterial secretion systems
Week 11: Bacterial toxins
Week 12: Antibiotics and resistance
Week 13: Bacterial posters

Note on Prerequisites:
MBB 328 with a minimum grade of C. MBB/HSCI 326 is no longer required for this course. Please email mbbugrad@sfu.ca to enroll in MBB 445 if you have not taken MBB/HSCI 326.


  • Paper presentation 30%
  • Poster 30%
  • Quizzes 30%
  • Poster participation/evaluations 10%



Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Department Undergraduate Notes:

  • For help with writing, learning and study strategies please contact the Student Learning Commons at
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:


SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html


Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.