Simon Fraser University
Engaging the World

Course Outlines

Spring 2024 - MBB 222 D100

Molecular Biology and Biochemistry (3)

Class Number: 5010

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 8 – Apr 12, 2024: Mon, Wed, Fri, 11:30 a.m.–12:20 p.m.
    Burnaby

  • Exam Times + Location:

    Apr 20, 2024
    Sat, 3:30–6:30 p.m.
    Burnaby

  • Prerequisites:

    or Corequisite CHEM 281.

Description

CALENDAR DESCRIPTION:

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis.

COURSE DETAILS:

TOPICS:

  • Introductory Organic Chemistry
  • Weak chemical interactions
  • Thermodynamics and catalysis
  • Amino acids, polypeptides
  • Protein structure, folding
  • Enzyme catalysis, protein function
  • DNA structure
  • DNA replication
  • DNA repair and mutagenesis
  • Mobile genetic elements
  • Chromosome structure, chromatin
  • Prokaryotic transcription
  • Eukaryotic transcription
  • RNA processing
  • Protein synthesis
  • Recombinant DNA and protein techniques

Grading

  • Two 40-minute Midterm Exams (25% each) 50%
  • One Cumulative Exam held in the Final Exam period 35%
  • Assignments 15%

Materials

MATERIALS + SUPPLIES:

Scientific calculator: SHARP EL-510RTB

REQUIRED READING:

Miesfeld, Roger L. and Megan M. McEvoy, Biochemistry, 2nd Edition. 2021.  W.W. Norton & Company.
ISBN: 9780393533507

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html

RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.