Spring 2024 - MBB 342 D100
Introductory Genomics and Bioinformatics (3)
Class Number: 5036
Delivery Method: In Person
Course Times + Location:
Jan 8 – Apr 12, 2024: Tue, 12:30–2:20 p.m.
1 778 782-5646
Prerequisites:MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.
Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research.
Approximately one week will be devoted to each of the following topics:
- What is Bioinformatics? What is Genomics? An overview and history
- Obtaining the data: Genome sequencing, genome assembly
- Organizing the data: Gene/genome databases, browsers and searching
- Sequence alignment and sequence similarity search
- Genome assembly and short read mapping
- Human genome variation – SNP, copy number and structural
- Transcriptomics/RNA sequencing, chromatin IP and promoter analysis
- Multiple sequence alignment, intro to evolutionary analysis
- Orthologs, paralogs/gene families, phylogenetic analysis
- Protein, network-based analysis and Systems Biology
- Microbial genomics and metagenomics of environmental/human microbiomes
- Human genomics and personalized medicine
- Plant and animal genomics in agriculture and aquaculture
- Lab assignments 40%
- Two non-cumulative written exams, the second held during the final exam period 40%
- Lab assignment/project 20%
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
- Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: email@example.com)
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html