Spring 2024 - MBB 443 D100
Protein Biogenesis and Degradation (3)
Class Number: 5488
Delivery Method: In Person
Course Times + Location:
Jan 8 – Apr 12, 2024: Wed, Fri, 10:30 a.m.–12:20 p.m.
1 778 782-5785
Prerequisites:MBB 321 and MBB 322, with a minimum grade of C.
A consideration of protein biogenesis (folding, assembly, and targeting to cellular compartments), modification, and degradation, and their roles in protein and cellular function.
Course Description The central dogma of molecular biology (DNA --› RNA --› PROTEIN) underscores two fundamental biological processes, transcription and translation, that are essential to life. Protein biogenesis (folding, assembly, targeting to the proper cellular compartment), and protein degradation represent two other equally important cellular activities. The emphasis in this course will be to review the literature on protein biogenesis and degradation, and explore the new and exciting developments that are just starting to uncover how mechanistically complex these processes are.
- Midterm I 25%
- Oral Presentation 15%
- Term Paper 20%
- Midterm II 40%
MATERIALS + SUPPLIES:
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