Simon Fraser University
Engaging the World

Course Outlines

Summer 2016 - MBB 729 G100

RNA-mediated Gene Regulation (3)

Class Number: 5502

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 9 – Aug 8, 2016: Wed, Fri, 2:30–4:20 p.m.
    Burnaby

  • Exam Times + Location:

    Aug 18, 2016
    Thu, 12:00–3:00 p.m.
    Burnaby

Description

CALENDAR DESCRIPTION:

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes. Students who have taken MBB 420 or MBB 829 under the same title cannot take this course for further credit.

COURSE DETAILS:

Topics

1.  RNA interference in plants and animals.
2.  CRISPR bacterial antiviral defense.
3.  Transcriptional and translational regulation – riboswitches, tmRNA, IRES elements, 6S RNA, etc.
4.  Post-transcriptional processing – editing, capping and splicing. Naturally occurring ribozymes.

Grading

  • Essay 50%
  • Final exam 25%
  • Presentation to undergraduates 25%

Materials

REQUIRED READING:

None.  This course is based on primary literature (journal articles). Supplementary material will be made available from selected texts or journal articles.

RECOMMENDED READING:

Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000. University Science Books.  This text is a great nucleic acid resource.
ISBN: 0-935702-49-0

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

SFU’s Academic Integrity web site contains information on what is meant by academic dishonesty and where you can find resources to help with your studies.  There is also a section on tutoring.  

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS