Summer 2020 - MBB 342 D100

Introductory Genomics and Bioinformatics (3)

Class Number: 2800

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 11 – Aug 10, 2020: Wed, 8:30–10:20 a.m.
    Burnaby

  • Prerequisites:

    MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.

Description

CALENDAR DESCRIPTION:

Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research.

COURSE DETAILS:

Course Structure:

Approximately one week will be devoted to each of the following topics:

  1. What is Bioinformatics? What is Genomics? An overview and history
  2. Obtaining the data: Genome sequencing, genome assembly
  3. Organizing the data: Gene/genome databases, browsers and searching
  4. Sequence alignment and sequence similarity search
  5. Genome assembly and short read mapping
  6. Human genome variation – SNP, copy number and structural
  7. Transcriptomics/RNA sequencing, chromatin IP and promoter analysis
  8. Multiple sequence alignment, intro to evolutionary analysis
  9. Orthologs, paralogs/gene families, phylogenetic analysis
  10. Protein, network-based analysis and Systems Biology
  11. Microbial genomics and metagenomics of environmental/human microbiomes
  12. Human genomics and personalized medicine
  13. Plant and animal genomics in agriculture and aquaculture

Grading

  • Lab assignments 40%
  • Final written exam 40%
  • Lab assignment/project 20%

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

TEACHING AT SFU IN SUMMER 2020

Please note that all teaching at SFU in summer term 2020 will be conducted through remote methods. Enrollment in this course acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as soon as possible to ensure that they are eligible and that approved accommodations and services are implemented in a timely fashion.