Spring 2022 - MBB 328 D100
Introduction to Microbial Pathogenesis (3)
Class Number: 2681
Delivery Method: In Person
Course Times + Location:
Tu 2:30 PM – 4:20 PM
SSCC 9000, Burnaby
Th 2:30 PM – 4:20 PM
AQ 3149, Burnaby
Exam Times + Location:
Apr 19, 2022
12:00 PM – 3:00 PM
WMC 2532, Burnaby
Prerequisites:MBB 231 with a minimum grade of C.
The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections - antibiotics, antiviral agents and vaccines - will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.
We will examine the molecular mechanisms by which microbial pathogens colonize the human body and cause disease. Emphasis will be placed on selected microbes and their structure/morphology, genetics, virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections, including antibiotics, antiviral agents and vaccines, will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.
Host immune response
Overview of virus structure
Selected viral pathogens:
- Polio virus
- Coronaviruses including SARS-CoV2
- Influenza virus
- Human immunodeficiency virus (HIV)
- Human papilloma virus (HPV)
- Herpes simplex virus (HSV)
Antiviral agents and resistance mechanisms
Selected bacterial pathogens:
- Listeria monocytogenes
- Streptococci, Enterococci, Staphylococcus aureus
- Pseudomonas aeruginosa
- pathogenic E. coli
- Klebsiella pneumoniae
Antibiotics and resistance mechanisms
Selected fungal pathogen & parasite
- Two midterm exams and a cumulative final exam 80%
- Assignments 20%
A custom textbook combo of two very popular textbooks (one for virology “Principles of Virology" and the other one for bacteriology, “Bacterial Pathogenesis").
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
- Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: email@example.com)
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TEACHING AT SFU IN SPRING 2022
Teaching at SFU in spring 2022 will involve primarily in-person instruction, with safety plans in place. Some courses will still be offered through remote methods, and if so, this will be clearly identified in the schedule of classes. You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).
Enrolling in a course acknowledges that you are able to attend in whatever format is required. You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.
Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (firstname.lastname@example.org or 778-782-3112) as early as possible in order to prepare for the spring 2022 term.