Spring 2022 - MBB 342 D100
Introductory Genomics and Bioinformatics (3)
Class Number: 2603
Delivery Method: In Person
Course Times + Location:
Tu 2:30 PM – 4:20 PM
AQ 4130, Burnaby
Prerequisites:MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.
Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research.
Approximately one week will be devoted to each of the following topics:
- What is Bioinformatics? What is Genomics? An overview and history
- Obtaining the data: Genome sequencing, genome assembly
- Organizing the data: Gene/genome databases, browsers and searching
- Sequence alignment and sequence similarity search
- Genome assembly and short read mapping
- Human genome variation – SNP, copy number and structural
- Transcriptomics/RNA sequencing, chromatin IP and promoter analysis
- Multiple sequence alignment, intro to evolutionary analysis
- Orthologs, paralogs/gene families, phylogenetic analysis
- Protein, network-based analysis and Systems Biology
- Microbial genomics and metagenomics of environmental/human microbiomes
- Human genomics and personalized medicine
- Plant and animal genomics in agriculture and aquaculture
- Lab assignments 40%
- Two non-cumulative written exams during class time (synchronous) 40%
- Lab assignment/project 20%
Department Undergraduate Notes:
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- Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: firstname.lastname@example.org)
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TEACHING AT SFU IN SPRING 2022
Teaching at SFU in spring 2022 will involve primarily in-person instruction, with safety plans in place. Some courses will still be offered through remote methods, and if so, this will be clearly identified in the schedule of classes. You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).
Enrolling in a course acknowledges that you are able to attend in whatever format is required. You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.
Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (email@example.com or 778-782-3112) as early as possible in order to prepare for the spring 2022 term.