Please note:

To view the Spring 2024 Academic Calendar, go to www.sfu.ca/students/calendar/2024/spring.html.

Department of Molecular Biology and Biochemistry | Faculty of Science Simon Fraser University Calendar | Summer 2024

Molecular Biology and Biochemistry Major

Bachelor of Science

The MBB major program provides a broad foundation in the life sciences from a biochemical, cellular, and molecular perspective. Flexibility in upper division course selection allows students to tailor the program to their own interests as well as meet the entry requirements for medical school and other professional and graduate programs.

Admission Requirements

Acceptance into and continuance in the program requires a minimum 2.5 cumulative grade point average (CGPA) upon completion of lower division required courses (not including the CMPT courses).

Secondary school students admitted via direct entry must achieve a 2.5 CGPA in all lower division required courses or be withdrawn from the program.

Students declaring the MBB major must have completed all required lower division courses with a CGPA of 2.5 in those courses.

Students may follow the requirements in effect when they were accepted into the program or students may take advantage of a new curriculum by changing requirement term at any time.

Prerequisite Course Grade

For a course to be accepted as fulfilling a prerequisite for any upper division MBB course, a student must have obtained a minimum grade of C unless otherwise noted.

Program Requirements

Students complete a total of 120 units, including lower and upper division requirements, and enough elective courses to total 120. Of these 120 units, 44 units must be in upper division courses.

Lower Division Requirements

Students complete all of

BISC 101 - General Biology (4)

Introduction to the molecular, cellular and physiological mechanisms of living organisms (microorganisms, plants, animals). Lecture and lab topics include cell structure and function, flow of genetic information, enzyme function, metabolism, whole organism form and function (circulation, gas exchange, nutrition, osmoregularion). BISC 101 and 102 can be taken in either order. Prerequisite: Biology 12 (or equivalent) with a minimum grade of C (or BISC 100 with a minimum grade of C-, or BISC 113 with a minimum grade of C+, or BPK 105 with a minimum grade of C+, or HSCI 100 with a minimum grade of C+); and Chemistry 12 (or equivalent) with a minimum grade of C (or CHEM 111 with a minimum grade of C-). Breadth-Science.

Section Instructor Day/Time Location
D100 Agata Becalska
May 6 – Aug 2, 2024: Tue, 10:30–11:20 a.m.
May 6 – Aug 2, 2024: Thu, 9:30–11:20 a.m.
Burnaby
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 1:30–2:20 p.m.
Burnaby
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 3:30–4:20 p.m.
Burnaby
Burnaby
D107 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 1:30–2:20 p.m.
Burnaby
Burnaby
D108 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
Burnaby
D109 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–1:20 p.m.
May 6 – Aug 2, 2024: Thu, 3:30–4:20 p.m.
Burnaby
Burnaby
BISC 102 - General Biology (4)

Introduction to evolution and ecology, focusing on the processes that shape the diversity of life on earth. Lecture and lab topics include: natural selection and other mechanisms of evolutionary change, phylogeny, genetics, speciation, behaviour, species interactions, population ecology, and ecosystems. BISC 101 and 102 may be taken in either order. Prerequisite: Biology 12 (or equivalent) with a minimum grade of C (or BISC 100 with a minimum grade of C-, or BISC 113 with a minimum grade of C+, or BPK 105 with a minimum grade of C+, or HSCI 100 with a minimum grade of C+). Breadth-Science.

Section Instructor Day/Time Location
D100 Miranda Meents
May 6 – Aug 2, 2024: Tue, Thu, 12:30–1:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 9:30 a.m.–12:20 p.m.
May 6 – Aug 2, 2024: Thu, 9:30–10:20 a.m.
Burnaby
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 9:30 a.m.–12:20 p.m.
May 6 – Aug 2, 2024: Thu, 10:30–11:20 a.m.
Burnaby
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 1:30–4:20 p.m.
May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
Burnaby
D104 May 6 – Aug 2, 2024: Tue, 1:30–4:20 p.m.
May 6 – Aug 2, 2024: Thu, 3:30–4:20 p.m.
Burnaby
Burnaby
D105 May 6 – Aug 2, 2024: Tue, 9:30–10:20 a.m.
May 6 – Aug 2, 2024: Thu, 9:30 a.m.–12:20 p.m.
Burnaby
Burnaby
D106 May 6 – Aug 2, 2024: Tue, 10:30–11:20 a.m.
May 6 – Aug 2, 2024: Thu, 9:30 a.m.–12:20 p.m.
Burnaby
Burnaby
BISC 202 - Genetics (3)

Principles and concepts of transmission of genetic information. Topics include: molecular basis of inheritance, interpretation of pedigrees, chromosomal mapping, linkage, crosses, epigenetics, and the regulation and flow of genetic information from DNA to proteins. Focus on problem-solving. Prerequisite: BISC 101 and 102, both with a minimum grade of C-.

Section Instructor Day/Time Location
D100 Kathleen Fitzpatrick
May 6 – Aug 2, 2024: Mon, Wed, Fri, 9:30–10:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Fri, 1:30–2:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Fri, 2:30–3:20 p.m.
Burnaby
CHEM 121 - General Chemistry and Laboratory I (4)

Atomic and molecular structure; chemical bonding; thermochemistry; elements; periodic table; gases liquids, solids, and solutions. This course includes a laboratory component. Prerequisite: Chemistry 12 with a minimum grade of C, or CHEM 109 or 111 with a minimum grade of C-. Students with credit for CHEM 120 or 125 may not take this course for further credit. Quantitative/Breadth-Science.

Section Instructor Day/Time Location
D100 Paul Li
May 6 – Aug 2, 2024: Mon, Wed, Fri, 10:30–11:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Wed, 9:30–10:20 a.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 12:30–1:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Thu, 10:30–11:20 a.m.
Burnaby
D105 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–12:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Fri, 9:30–10:20 a.m.
Burnaby
D107 May 6 – Aug 2, 2024: Fri, 11:30 a.m.–12:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Fri, 12:30–1:20 p.m.
Burnaby
D109 May 6 – Aug 2, 2024: Fri, 1:30–2:20 p.m.
Burnaby
D110 May 6 – Aug 2, 2024: Wed, 9:30–10:20 a.m.
Burnaby
D111 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D112 May 6 – Aug 2, 2024: Fri, 11:30 a.m.–12:20 p.m.
Burnaby
LA02 Garry Mund
May 6 – Aug 2, 2024: Tue, 8:30 a.m.–12:20 p.m.
Burnaby
LA03 Garry Mund
May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
LB02 Garry Mund
May 6 – Aug 2, 2024: Tue, 8:30 a.m.–12:20 p.m.
Burnaby
LB03 Garry Mund
May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
LE01 TBD
CHEM 122 - General Chemistry II (2)

Chemical equilibria; electrochemistry; chemical thermodynamics; kinetics. Students who intend to take further laboratory courses in chemistry should take CHEM 122 concurrently with CHEM 126. Prerequisite: CHEM 120 or 121 with a minimum grade of C-. Students with credit for CHEM 124 or CHEM 180 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Hogan Yu
May 6 – Aug 2, 2024: Mon, Wed, Fri, 12:30–1:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Wed, 9:30–10:20 a.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 10:30–11:20 a.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Wed, 1:30–2:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Thu, 10:30–11:20 a.m.
Burnaby
D106 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–12:20 p.m.
Burnaby
D107 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–12:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Thu, 12:30–1:20 p.m.
Burnaby
D109 May 6 – Aug 2, 2024: Fri, 11:30 a.m.–12:20 p.m.
Burnaby
D110 May 6 – Aug 2, 2024: Fri, 1:30–2:20 p.m.
Burnaby
D111 May 6 – Aug 2, 2024: Fri, 2:30–3:20 p.m.
Burnaby
CHEM 126 - General Chemistry Laboratory II (2)

Experiments in chemical equilibrium, acids and bases, qualitative analysis, electrochemistry and chemical kinetics. Prerequisite: CHEM 121 with a minimum grade of C-. Corequisite: CHEM 122. Quantitative.

Section Instructor Day/Time Location
LA04 Garry Mund
May 6 – Aug 2, 2024: Wed, 1:30–5:20 p.m.
Burnaby
LA06 Garry Mund
May 6 – Aug 2, 2024: Thu, 1:30–5:20 p.m.
Burnaby
CHEM 281 - Organic Chemistry and Laboratory I (4)

Structure, bonding, physical and chemical properties of simple organic compounds. Introduction to spectroscopy. Kinetics and mechanisms of organic reactions. This course includes a laboratory component. Prerequisite: CHEM 121 with a minimum grade of C-. Corequisite: CHEM 122. Students with credit for CHEM 280 or CHEM 285 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 M Khaled Arafeh
May 6 – Aug 2, 2024: Mon, Wed, Fri, 10:30–11:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Wed, 9:30–10:20 a.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 12:30–1:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Thu, 9:30–10:20 a.m.
Burnaby
D105 May 6 – Aug 2, 2024: Thu, 11:30 a.m.–12:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Fri, 9:30–10:20 a.m.
Burnaby
D107 May 6 – Aug 2, 2024: Fri, 11:30 a.m.–12:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Fri, 12:30–1:20 p.m.
Burnaby
D109 May 6 – Aug 2, 2024: Wed, 9:30–10:20 a.m.
Burnaby
D110 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D111 May 6 – Aug 2, 2024: Fri, 9:30–10:20 a.m.
Burnaby
D112 May 6 – Aug 2, 2024: Thu, 12:30–1:20 p.m.
Burnaby
LA03 M Khaled Arafeh
May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
LA06 M Khaled Arafeh
May 6 – Aug 2, 2024: Thu, 1:30–5:20 p.m.
Burnaby
LB06 M Khaled Arafeh
May 6 – Aug 2, 2024: Thu, 1:30–5:20 p.m.
Burnaby
LB07 M Khaled Arafeh
May 6 – Aug 2, 2024: Fri, 1:30–5:20 p.m.
Burnaby
LE01 TBD
CHEM 286 - Organic Chemistry Laboratory II (2)

Laboratory work chosen to complement the lecture course. Prerequisite: CHEM 281 with a minimum grade of C-. Corequisite: CHEM 282 or 283. Quantitative.

Section Instructor Day/Time Location
LA01 Uwe Kreis
May 6 – Jun 17, 2024: Mon, Wed, 1:30–5:20 p.m.
Burnaby
MBB 222 - Molecular Biology and Biochemistry (3)

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis. Prerequisite: or Corequisite CHEM 281.

Section Instructor Day/Time Location
D100 Irina Kovalyova
May 6 – Aug 2, 2024: Mon, Wed, Fri, 11:30 a.m.–12:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Mon, 2:30–3:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Mon, 3:30–4:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 12:30–1:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
MBB 229 - Introductory Molecular Biology and Biochemistry Laboratory (2)

Practical course providing hands-on experience in fundamental molecular biology and biochemistry techniques including DNA isolation, restriction enzyme digestion, transformation, polymerase chain reaction, DNA and protein electrophoresis and immunofluorescence. Prerequisite: or Corequisite: MBB 222. Students who have taken MBB 308 or MBB 309 first may not then take this course for further credit.

Section Instructor Day/Time Location
LA01 Irina Kovalyova
May 6 – Aug 2, 2024: Thu, 1:30–5:20 p.m.
Burnaby
LA02 Irina Kovalyova
May 6 – Aug 2, 2024: Fri, 1:30–5:20 p.m.
Burnaby
MBB 231 - Cellular Biology and Biochemistry (3)

A study of the molecular processes which underlie cell structure and function, integrating ultrastructural, physiological and biochemical approaches. Modern techniques used in the analysis of organelle and cell function are integral parts of the course. Prerequisite: MBB 222, BISC 101, CHEM 281 with grades of C- or better. Corequisite or Prerequisite: CHEM 282 or CHEM 283.

Section Instructor Day/Time Location
D100 Ingrid Northwood
May 6 – Aug 2, 2024: Mon, Wed, 11:30 a.m.–12:20 p.m.
May 6 – Aug 2, 2024: Fri, 11:30 a.m.–12:20 p.m.
Burnaby
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 10:30–11:20 a.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 11:30 a.m.–12:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Mon, 2:30–3:20 p.m.
Burnaby

and one of

CHEM 282 - Organic Chemistry II (2)

Polyfunctional organic compounds and complex organic reactions. Introduction to natural products. Prerequisite: CHEM 281 with a minimum grade of C-. Students with credit for CHEM 283 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Uwe Kreis
May 6 – Jun 17, 2024: Mon, Wed, 9:30–11:20 a.m.
Burnaby
D101 May 6 – Jun 17, 2024: Tue, 9:30–11:20 a.m.
Burnaby
D102 May 6 – Jun 17, 2024: Tue, 11:30 a.m.–1:20 p.m.
Burnaby
D103 May 6 – Jun 17, 2024: Tue, 1:30–3:20 p.m.
Burnaby
D104 May 6 – Jun 17, 2024: Thu, 9:30–11:20 a.m.
Burnaby
D105 May 6 – Jun 17, 2024: Thu, 11:30 a.m.–1:20 p.m.
Burnaby
D106 May 6 – Jun 17, 2024: Thu, 1:30–3:20 p.m.
Burnaby
D107 May 6 – Jun 17, 2024: Tue, 9:30–11:20 a.m.
Burnaby
D108 May 6 – Jun 17, 2024: Tue, 11:30 a.m.–1:20 p.m.
Burnaby
CHEM 283 - Organic Chemistry IIb (3)

An advanced treatment of Organic Chemistry II. Topics include dienes and their reactivity, conjugation and aromaticity, aromatic substitution reactions, carboxylic acids and their derivatives, ketones and aldehydes, biological molecules, radical reactions, organometallic reagents, pericyclic reactions and planning multi-step synthesis. Prerequisite: CHEM 281 with a minimum grade of C-. Students with credit for CHEM 282 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Uwe Kreis
May 6 – Jun 17, 2024: Mon, Wed, 9:30–11:20 a.m.
May 6 – Jun 17, 2024: Fri, 9:30–11:20 a.m.
Burnaby
Burnaby
D101 May 6 – Jun 17, 2024: Thu, 9:30–11:20 a.m.
Burnaby
D102 May 6 – Jun 17, 2024: Thu, 11:30 a.m.–1:20 p.m.
Burnaby

and one of

CMPT 120 - Introduction to Computing Science and Programming I (3)

An elementary introduction to computing science and computer programming, suitable for students with little or no programming background. Students will learn fundamental concepts and terminology of computing science, acquire elementary skills for programming in a high-level language, e.g. Python. The students will be exposed to diverse fields within, and applications of computing science. Topics will include: pseudocode; data types and control structures; fundamental algorithms; recursion; reading and writing files; measuring performance of algorithms; debugging tools; basic terminal navigation using shell commands. Treatment is informal and programming is presented as a problem-solving tool. Prerequisite: BC Math 12 or equivalent is recommended. Students with credit for CMPT 102, 128, 130 or 166 may not take this course for further credit. Students who have taken CMPT 125, 129, 130 or 135 first may not then take this course for further credit. Quantitative/Breadth-Science.

Section Instructor Day/Time Location
D100 Gregory Baker
May 6 – Aug 2, 2024: Mon, Wed, Fri, 10:30–11:20 a.m.
Burnaby
MBB 110 - Data Analysis for Molecular Biology and Biochemistry (3) *

Introductory data analysis focusing on molecular biology data sets and examples and including basic programming skills using Python and basic statistics skills using R. Prerequisite: MATH 12 or equivalent is recommended. Students with credit for MBB 243 may not take this course for further credit. CMPT 120 will be accepted in lieu of MBB 110.

and one of

MATH 150 - Calculus I with Review (4)

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Topics as for Math 151 with a more extensive review of functions, their properties and their graphs. Recommended for students with no previous knowledge of Calculus. In addition to regularly scheduled lectures, students enrolled in this course are encouraged to come for assistance to the Calculus Workshop (Burnaby), or Math Open Lab (Surrey). Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least B+, or MATH 100 with a grade of at least B-, or achieving a satisfactory grade on the Simon Fraser University Calculus Readiness Test. Students with credit for either MATH 151, 154 or 157 may not take MATH 150 for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Mahsa Faizrahnemoon
May 6 – Aug 2, 2024: Mon, Wed, Fri, 1:30–2:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 8:30–9:20 a.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 9:30–10:20 a.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 10:30–11:20 a.m.
Burnaby
OP01 TBD
MATH 151 - Calculus I (3)

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Logarithmic and exponential functions, trigonometric functions, inverse functions. Limits, continuity, and derivatives. Techniques of differentiation, including logarithmic and implicit differentiation. The Mean Value Theorem. Applications of differentiation including extrema, curve sketching, Newton's method. Introduction to modeling with differential equations. Polar coordinates, parametric curves. Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least A, or MATH 100 with a grade of at least B, or achieving a satisfactory grade on the Simon Fraser University Calculus Readiness Test. Students with credit for either MATH 150, 154 or 157 may not take MATH 151 for further credit. Quantitative.

MATH 154 - Mathematics for the Life Sciences I (3)

Designed for students specializing in the life sciences. Topics include: limits, growth rate and the derivative; elementary functions, optimization and approximation methods, and their applications, integration, and differential equations; mathematical models of biological processes and their implementation and analysis using software. Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least B, or MATH 100 with a grade of at least C-, or achieving a satisfactory grade on the Simon Fraser University Calculus Readiness Test. Students with credit for either MATH 150, 151 or 157 may not take MATH 154 for further credit. Quantitative.

and one of

PHYS 101 - Physics for the Life Sciences I (3)

Force and motion, conservation of energy and momentum, fluids, properties of soft matter and thermal physics with applications taken from the life sciences. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154 or 157; BISC 100 or 101 or 102. Recommended Corequisite: PHYS 132. Students with credit for PHYS 120, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

Section Instructor Day/Time Location
D100 Andrew Debenedictis
May 6 – Aug 2, 2024: Mon, Wed, Fri, 9:30–10:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 4:30–5:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Wed, 4:30–5:20 p.m.
Burnaby
D107 May 6 – Aug 2, 2024: Wed, 5:30–6:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
D109 May 6 – Aug 2, 2024: Thu, 3:30–4:20 p.m.
Burnaby
D110 May 6 – Aug 2, 2024: Thu, 4:30–5:20 p.m.
Burnaby
D111 May 6 – Aug 2, 2024: Thu, 5:30–6:20 p.m.
Burnaby
OP01 May 6 – Aug 2, 2024: Mon, 3:30–5:20 p.m.
Burnaby
PHYS 120 - Mechanics and Modern Physics (3)

A general calculus-based introduction to mechanics. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154. Recommended Corequisite: PHYS 132. Students with credit for PHYS 101, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

PHYS 125 - Mechanics and Special Relativity (3)

A course in mechanics and modern physics designed for students who want to study translational and rotational dynamics, conservation laws, and oscillations in depth and gain additional insight into foundations of special relativity and select topics in modern physics. Prerequisite: Permission of the department. Corequisite: MATH 151. Recommended Corequisite: PHYS 132. Students with credit for PHYS 101, 120 or PHYS 140 may not take PHYS 125 for further credit. Quantitative.

PHYS 140 - Studio Physics - Mechanics and Modern Physics (4)

A general calculus-based introduction to mechanics taught in an integrated lecture-laboratory environment. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12, or PHYS 100 or equivalent, with a minimum grade of C-. Corequisite: MATH 150 or 151 or 154. Students with credit for PHYS 125 or 120 or 101 may not take this course for further credit. Quantitative/Breadth-Science.

and one of

STAT 201 - Statistics for the Life Sciences (3)

Research methodology and associated statistical analysis techniques for students with training in the life sciences. Intended to be particularly accessible to students who are not specializing in Statistics. Prerequisite: Recommended: 30 units. Students cannot obtain credit for STAT 201 if they already have credit for - or are taking concurrently - STAT 101, 203, 205, 285, or any upper division STAT course. Quantitative.

Section Instructor Day/Time Location
D100 Brad McNeney
May 6 – Aug 2, 2024: Wed, 1:30–2:20 p.m.
May 6 – Aug 2, 2024: Fri, 12:30–2:20 p.m.
Burnaby
Burnaby
OL01 Wei Lin
Online
OP01 TBD
STAT 270 - Introduction to Probability and Statistics (3)

Basic laws of probability, sample distributions. Introduction to statistical inference and applications. Prerequisite: or Corequisite: MATH 152 or 155 or 158, with a minimum grade of C-. Students wishing an intuitive appreciation of a broad range of statistical strategies may wish to take STAT 100 first. Quantitative.

Section Instructor Day/Time Location
D100 Sessional
May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
May 6 – Aug 2, 2024: Fri, 10:30 a.m.–12:20 p.m.
Burnaby
Burnaby
OL01 Gamage Perera
Online
OP01 TBD

and two courses with different subjects from the following list, excluding courses already taken.

CHEM 210 - Introduction to Analytical Chemistry (2)

The principles of analytical chemistry and their practical application to solution samples. Titrimetric and electrochemical methods. This course has the same lecture component as CHEM 215 but no laboratory work. Prerequisite: CHEM 122 with a minimum grade of C-. Students with credit for CHEM 215 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Dev Sharma
May 6 – Aug 2, 2024: Mon, Wed, Fri, 11:30 a.m.–12:20 p.m.
Burnaby
and CHEM 216 - Introduction to Analytical Chemistry Laboratory (2)

Experiments in analytical chemistry, including analysis of solution samples, titrimetric and electroanalytical methods. This course has the same laboratory component as CHEM 215. Prerequisite: CHEM 122 and CHEM 126, both with a minimum grade of C-. Corequisite: CHEM 210. Students with credit for CHEM 215 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
LA01 Dev Sharma
May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
LA02 Dev Sharma
May 6 – Aug 2, 2024: Fri, 1:30–5:20 p.m.
Burnaby
CHEM 380 - Chemical and Instrumental Methods of Identification of Organic Compounds (4)

Basic principles of infrared, ultraviolet, nuclear magnetic resonance and mass spectroscopy as applied to the identification of organic compounds. Prerequisite: (CHEM 282 or 283 or 284) and CHEM 286, both with a minimum grade of C-, or permission of the department.

PHYS 102 - Physics for the Life Sciences II (3)

Waves and optics; electricity and magnetism; modern physics emphasizing radioactivity, with applications taken from the life sciences. Prerequisite: PHYS 101 or 120 or 125 or 140; MATH 150 or 151 or 154 or 157; both with a minimum grade of C-. Corequisite: BISC 100 or 101 or 102. Recommended Corequisites: MATH 152, 155 or 158; PHYS 133. Students with credit for PHYS 121, 126, or 141 may not take this course for further credit. Quantitative/Breadth-Science.

Section Instructor Day/Time Location
D100 Sessional
May 6 – Aug 2, 2024: Mon, Wed, Fri, 9:30–10:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 4:30–5:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
D107 May 6 – Aug 2, 2024: Wed, 4:30–5:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Wed, 5:30–6:20 p.m.
Burnaby
D109 May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
D110 May 6 – Aug 2, 2024: Thu, 3:30–4:20 p.m.
Burnaby
D111 May 6 – Aug 2, 2024: Thu, 4:30–5:20 p.m.
Burnaby
OPL May 6 – Aug 2, 2024: Mon, 12:30–2:20 p.m.
Burnaby
PHYS 121 - Optics, Electricity and Magnetism (3)

A general calculus-based introduction to electricity, magnetism and optics. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or 125 or 140, with a minimum grade of C-, or PHYS 101 with a minimum grade of B. Corequisite: MATH 152 or 155. Recommended Corequisite: PHYS 133. Students with credit for PHYS 102, 126 or 141 may not take this course for further credit. Quantitative/Breadth-Science.

Section Instructor Day/Time Location
D100 Michael Chen
May 6 – Aug 2, 2024: Mon, Wed, Fri, 9:30–10:20 a.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 4:30–5:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Wed, 2:30–3:20 p.m.
Burnaby
D105 May 6 – Aug 2, 2024: Wed, 3:30–4:20 p.m.
Burnaby
D106 May 6 – Aug 2, 2024: Wed, 4:30–5:20 p.m.
Burnaby
D108 May 6 – Aug 2, 2024: Thu, 2:30–3:20 p.m.
Burnaby
PHYS 126 - Electricity, Magnetism and Light (3)

A course in electromagnetism designed for students who want to study electric charge and current, electric and magnetic fields, circuits, electromagnetic interactions in depth and gain additional insight into Maxwell’s equations, electromagnetic waves, and wave-particle duality. Prerequisite: PHYS 125 with a minimum grade of C- or permission of the department. Corequisite: MATH 152. Recommended Corequisite: PHYS 133. Students with credit in PHYS 102, 121 or 141 may not take this course for further credit. Quantitative.

PHYS 141 - Studio Physics - Optics, Electricity and Magnetism (4)

A general calculus-based introduction to electricity, magnetism and optics taught in an integrated lecture-laboratory environment. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or PHYS 125 or PHYS 140, with a minimum grade of C-, or PHYS 101 with a minimum grade of B. Corequisite: MATH 152 or MATH 155. Students with credit for PHYS 126 or 121 or 102 may not take this course for further credit. Quantitative/Breadth-Science.

MATH 152 - Calculus II (3)

Riemann sum, Fundamental Theorem of Calculus, definite, indefinite and improper integrals, approximate integration, integration techniques, applications of integration. First-order separable differential equations and growth models. Sequences and series, series tests, power series, convergence and applications of power series. Prerequisite: MATH 150 or 151, with a minimum grade of C-; or MATH 154 or 157 with a grade of at least B. Students with credit for MATH 155 or 158 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Stephen Choi
May 6 – Aug 2, 2024: Mon, Wed, Fri, 8:30–9:20 a.m.
Burnaby
OP01 TBD
MATH 155 - Mathematics for the Life Sciences II (3)

Designed for students specializing in the life sciences. Topics include: vectors and matrices, partial derivatives, multi-dimensional integrals, systems of differential equations, compartment models, graphs and networks, and their applications to the life sciences; mathematical models of multi-component biological processes and their implementation and analysis using software. Prerequisite: MATH 150, 151 or 154, with a minimum grade of C-; or MATH 157 with a grade of at least B. Students with credit for MATH 152 or 158 may not take this course for further credit. Quantitative.

Section Instructor Day/Time Location
D100 Veselin Jungic
May 6 – Aug 2, 2024: Mon, Wed, Fri, 8:30–9:20 a.m.
Burnaby
OPO1 TBD

* Recommended

Upper Division Requirements

Students complete all of

MBB 308 - Molecular Biology Laboratory (3)

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: or corequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Section Instructor Day/Time Location
D100 Stephanie Vlachos
May 6 – Aug 2, 2024: Mon, 2:30–4:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 1:30–5:20 p.m.
Burnaby
MBB 309W - Biochemistry Laboratory (4)

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

MBB 321 - Intermediary Metabolism (3)

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states. Prerequisite: MBB 231, with a minimum grade of C.

MBB 322 - Molecular Physiology (3)

Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, neuronal transmission and the signal transduction pathways that integrate them. Prerequisite: MBB 231, with a minimum grade of C.

MBB 331 - Molecular Biology (4)

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction. Prerequisite: MBB 231, and BISC 202, with a minimum grade of C.

Section Instructor Day/Time Location
D100 Sophie Sneddon
May 6 – Aug 2, 2024: Tue, Thu, 10:30 a.m.–12:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 9:30–10:20 a.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 12:30–1:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Thu, 9:30–10:20 a.m.
Burnaby

and a minimum of six courses chosen from the following list, three of which must be 400-level courses. There is no upper limit on the quantity in this list that can be completed.

HSCI 442 - Immunology Laboratory (4)

Laboratory methods in immunology. Focus on the vertebrate immune system and the molecular and cellular principles underlying immune recognition. Experimental methods designed to combine serology, biochemistry, molecular biology, cell biology and genetics as a basis for understanding immunological aspects of health and disease. Prerequisite: HSCI 326 or MBB 326, and one of BISC 303, BISC 357, MBB 308, or MBB 309W, all with a minimum grade of C-.

MBB 323 - Introduction to Physical Biochemistry (3)

Introduction to physical biochemistry including thermodynamics, spectroscopic principles and applications, and molecular transport and interactions. The physical properties and structure determination of biomolecules will be emphasized. Prerequisite: MATH 152 (or 155), PHYS 121 (or 102, or 126, or 141), CHEM 122 (or 102), MBB 222 with a minimum grade of C.

MBB 324 - Protein Biochemistry (3)

An exploration of the fundamental aspects of proteins; their chemical and physical nature, their synthesis, stability and turnover, as well as their structure and function. Methods of protein analysis and structure determination will be presented. Prerequisite: MBB 222 with a minimum grade of C.

MBB 326 - Introduction to the Immune System (3)

Introduction to the structure and function of the immune system and how this system protects against microbial infections. Innate immune responses, including the function of innate immune cells, receptors and complement. Adaptive immune responses, including the organization of lymphoid organs, development and function of T and B cells, and antibodies. Prerequisite: MBB 231 with a minimum grade of C. Students with credit for HSCI 426, MBB 426 or HSCI 326 may not take this course for further credit.

Section Instructor Day/Time Location
D100 Ingrid Northwood
May 6 – Aug 2, 2024: Mon, Wed, Fri, 1:30–2:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Mon, 11:30 a.m.–12:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
MBB 328 - Introduction to Microbial Pathogenesis (3)

The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections - antibiotics, antiviral agents and vaccines - will be discussed in detail. Prerequisite: MBB 231 with a minimum grade of C. Students with credit for MBB 428 may not take this course for further credit.

MBB 342 - Introductory Genomics and Bioinformatics (3)

Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research. Prerequisite: MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.

MBB 402 - Cell Signalling in Development and Disease (3)

A mechanistic study of signal transduction pathways, their roles in development and disease with an emphasis on current literature. Prerequisite: MBB 322 or BISC 302W or BISC 333, with a minimum grade of C.

MBB 420 - Selected Topics in Contemporary Biochemistry (3)

The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: Will be announced before the start of the term and will depend upon the nature of the topic offered.

MBB 421 - Nucleic Acids (3)

Recent literature is examined for insights into the structure and properties of DNA and RNA, drawing on a variety of biochemical, chemical and molecular biological perspectives. Prerequisite: MBB 331 with a minimum grade of C.

MBB 422 - Biomembranes (3)

A review of recent research on the structure, dynamics, function and biosynthesis of membranes, membrane lipids and proteins. Prerequisite: MBB 322 and MBB 309W with a minimum grade of C, MBB 324 as a pre or co-requisite.

MBB 423 - Protein Structure and Function (3)

Mechanistic principles for how protein molecules achieve diverse functions such as chemical catalysis and conformational switching. Students will learn to critique hypotheses about structural mechanisms, and to interpret the primary literature reporting on structural evidence from X-ray diffraction and spectroscopy. Prerequisite: MBB 323 or MBB 324, with a minimum grade of C.

MBB 424 - Membrane Transport Mechanisms (3)

Structure and function of molecules that mediate transport across membranes including channels, carriers, and pumps. Primary literature from the fields of biochemistry and physiology will be explored through lectures and independent study. Prerequisite: MBB 321, and any two of MBB 322, MBB 323, MBB 324, CHEM 360, with a minimum grade of C, or permission of the instructor.

MBB 427 - Immune Responses in Health and Disease (3)

Defects in the immunologic response to bacterial, viral and parasitic infections. The mechanisms of action of vaccines. The causes of immune-mediated diseases, such as autoimmune diseases, hypersensitivity reactions (including asthma and allergy) and organ transplant rejection. The reaction of the immune system to cancer and immunotherapy for cancer. Prerequisite: One of MBB 326, HSCI 326, MBB 426 or HSCI 426, with a minimum grade of C, or permission of the instructor. Students with credit for HSCI 427 cannot take MBB 427 for credit.

MBB 429 - RNA-mediated Gene Regulation (3)

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes. Prerequisite: MBB 331 with a minimum grade of C.

Section Instructor Day/Time Location
D100 Peter Unrau
Sophie Sneddon
May 6 – Aug 2, 2024: Wed, Fri, 8:30–10:20 a.m.
Burnaby
MBB 430 - Mechanisms of Secretory Transport (3)

Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells; processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of vesicle transport and membrane fusion; role in signal transduction and disease. Prerequisite: MBB 322 and MBB 331, with a minimum grade of C.

MBB 431 - Cells and the Environment (3)

The cellular processes at the interface of cells and the environment will be explored in-depth. Through the use of lectures and group discussions and an emphasis on the primary literature, the focus will be on recent developments in molecular cell biology through the study of symbiosis and adaptation. Prerequisite: MBB 322 and 331, with a minimum grade of C.

MBB 432 - Advanced Molecular Biology Techniques (4)

Laboratory with accompanying lectures designed to give practical experience in advanced contemporary molecular biology techniques. Projects will involve recombinant gene and protein manipulations to investigate the dynamics of proteins within living cells. Prerequisite: MBB 308 and MBB 331, all with a minimum grade of C, or permission of instructor. Recommended: MBB 309W.

Section Instructor Day/Time Location
D100 Chris Beh
May 6 – Aug 2, 2024: Wed, 1:30–5:20 p.m.
Burnaby
MBB 433 - Epithelial Cell Biology (3)

Emerging concepts in epithelial cell biology, including the establishment and maintenance of epithelial cell polarity and cell adhesion leading to the sculpting of developing organisms, roles in wound healing, birth defects and microbial defense, and insights into the maintenance of epithelia by stem cells will be explored. Prerequisite: MBB 331 or BISC 333, with a minimum grade of C.

MBB 436 - Gene Expression (3)

Lectures and student presentations will cover the wide range of ways in which organisms (primarily eukaryotes) regulate gene expression along the pathway from DNA to protein. Prerequisite: MBB 331, with a minimum grade of C.

MBB 438 - Human Molecular Genetics (3)

Recent advances in human molecular genetics including genome analysis, gene therapy, genetic testing, and studies of genetic disorders. Prerequisite: MBB 331, with a minimum grade of C.

MBB 440 - Selected Topics in Contemporary Molecular Biology (3)

The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: will depend upon the nature of the topic offered.

MBB 441 - Bioinformatics (3)

Examining the use of, and theory behind, bioinformatic software and algorithms for the analysis of macromolecular data. Includes consideration of recent literature and discussion of ethics in method development and analysis. Prerequisite: MBB 243 or 3 units of CMPT or equivalent with a minimum grade of C, or permission of the instructor; MBB 331 and MBB 342, with a minimum grade of C.

MBB 443 - Protein Biogenesis and Degradation (3)

A consideration of protein biogenesis (folding, assembly, and targeting to cellular compartments), modification, and degradation, and their roles in protein and cellular function. Prerequisite: MBB 321 and MBB 322, with a minimum grade of C.

MBB 445 - Advanced Microbial Pathogenesis (3)

Recent advances in microbial pathogenesis with an emphasis on primary literature. Prerequisite: MBB 328 and either MBB 326 or HSCI 326, all with a minimum grade of C.

MBB 446 - The Molecular Biology of Cancer (3)

An examination of the molecular mechanisms that contribute to tumor formation, the hallmarks of cancer and their relationship to therapeutic strategies. Prerequisite: MBB 322 and 331, with a minimum grade of C, or permission of the instructor.

MBB 447 - Stem Cells - Current Trends (3)

Foundational biology of stem cell populations, technological advances, current and potential therapeutic applications. Prerequisite: MBB 322 or BISC 333, with a minimum grade of C. Students with credit for BISC 447 may not take this course for further credit. Students with credit for MBB 440 or BISC 472 under the title "Stem Cell Biology and Applications" may not take this course for further credit.

MBB 460 - Selected Topics in Bioinformatics and Genomics (3)

The topics in this course will vary from term to term, depending on faculty availability and student interest. Students may repeat this course for further credit under a different topic. Prerequisite: Will vary depending on the topic.

MBB 461 - Comparative Genomics (3)

Examination of the fundamentals of comparative genomics, identification and activity of functional elements in genomes, inter- and intra-species comparisons, relationship of genomic to phenotypic variation, and personalized genomics are among the topics to be explored. Comparison of genome data has impacts on medicine and many other fields of the life sciences. Prerequisite: MBB 331 and MBB 342, with a minimum grade of C. Students who have completed MBB 440 Comparative Genomics may not complete this course for further credit.

MBB 462 - Human Genomics (3)

The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues. Prerequisite: MBB 331 and MBB 342, with a minimum grade of C. Students with credit for MBB 440 with this same course title may not complete this course for further credit.

Section Instructor Day/Time Location
D100 Sophie Sneddon
May 6 – Aug 2, 2024: Tue, Thu, 8:30–10:20 a.m.
Burnaby
MBB 463 - Forensic Genomics (3)

A focus on the molecular and genomic biology associated with forensic science, including genome structure, genotyping, genetic analysis of DNA fingerprints, DNA data bases and CODIS, Y STRs. mtDNA and ethical considerations of DNA typing. Prerequisite: MBB 331, with a minimum grade of C.

MBB 464 - From Genome to System (3)

Methods that enable the integration of Biochemical, Genetic and Genomic knowledge (BiGG) to reconstruct a genomic scale network that defines the metabolic physiology of an organism will be explored. Applications of these approaches in the fields of microbial evolution, interaction networks, genetic engineering and drug discovery will be discussed. Prerequisite: MBB 331 and MBB 342.

MBB 465 - Cancer Genomics (3)

Our understanding of the role of genetic and epigenetic changes in the formation of human cancers continues to be advanced by genomic technologies. Current techniques for studying cancer genomes and how heritable changes can lead to treatment resistance will be discussed. Prerequisite: MBB 331 and MBB 342 with a minimum grade of C or permission of the instructor. Students with credit for MBB 460 under the title "Cancer Genomics" may not take this course for further credit.

MBB 478 - Seminar in Molecular Epidemiology of Infectious Diseases (3)

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. Prerequisite: HSCI 326 or MBB 326 or MBB 331, with a minimum grade of C, or HSCI 338 with a minimum grade of C-. Students with credit for HSCI 478 may not take this course for further credit.

Concentration in Infection and Immunity

Students who choose this concentration will complete all of

MBB 308 - Molecular Biology Laboratory (3)

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: or corequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Section Instructor Day/Time Location
D100 Stephanie Vlachos
May 6 – Aug 2, 2024: Mon, 2:30–4:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 1:30–5:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Wed, 1:30–5:20 p.m.
Burnaby
MBB 309W - Biochemistry Laboratory (4)

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

MBB 321 - Intermediary Metabolism (3)

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states. Prerequisite: MBB 231, with a minimum grade of C.

MBB 322 - Molecular Physiology (3)

Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, neuronal transmission and the signal transduction pathways that integrate them. Prerequisite: MBB 231, with a minimum grade of C.

MBB 324 - Protein Biochemistry (3)

An exploration of the fundamental aspects of proteins; their chemical and physical nature, their synthesis, stability and turnover, as well as their structure and function. Methods of protein analysis and structure determination will be presented. Prerequisite: MBB 222 with a minimum grade of C.

MBB 326 - Introduction to the Immune System (3)

Introduction to the structure and function of the immune system and how this system protects against microbial infections. Innate immune responses, including the function of innate immune cells, receptors and complement. Adaptive immune responses, including the organization of lymphoid organs, development and function of T and B cells, and antibodies. Prerequisite: MBB 231 with a minimum grade of C. Students with credit for HSCI 426, MBB 426 or HSCI 326 may not take this course for further credit.

Section Instructor Day/Time Location
D100 Ingrid Northwood
May 6 – Aug 2, 2024: Mon, Wed, Fri, 1:30–2:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Mon, 11:30 a.m.–12:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 2:30–3:20 p.m.
Burnaby
D103 May 6 – Aug 2, 2024: Wed, 11:30 a.m.–12:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
MBB 328 - Introduction to Microbial Pathogenesis (3)

The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections - antibiotics, antiviral agents and vaccines - will be discussed in detail. Prerequisite: MBB 231 with a minimum grade of C. Students with credit for MBB 428 may not take this course for further credit.

MBB 331 - Molecular Biology (4)

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction. Prerequisite: MBB 231, and BISC 202, with a minimum grade of C.

Section Instructor Day/Time Location
D100 Sophie Sneddon
May 6 – Aug 2, 2024: Tue, Thu, 10:30 a.m.–12:20 p.m.
Burnaby
D101 May 6 – Aug 2, 2024: Tue, 3:30–4:20 p.m.
Burnaby
D102 May 6 – Aug 2, 2024: Tue, 9:30–10:20 a.m.
Burnaby
D103 May 6 – Aug 2, 2024: Tue, 12:30–1:20 p.m.
Burnaby
D104 May 6 – Aug 2, 2024: Thu, 9:30–10:20 a.m.
Burnaby
MBB 342 - Introductory Genomics and Bioinformatics (3)

Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research. Prerequisite: MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.

and two of

MBB 427 - Immune Responses in Health and Disease (3)

Defects in the immunologic response to bacterial, viral and parasitic infections. The mechanisms of action of vaccines. The causes of immune-mediated diseases, such as autoimmune diseases, hypersensitivity reactions (including asthma and allergy) and organ transplant rejection. The reaction of the immune system to cancer and immunotherapy for cancer. Prerequisite: One of MBB 326, HSCI 326, MBB 426 or HSCI 426, with a minimum grade of C, or permission of the instructor. Students with credit for HSCI 427 cannot take MBB 427 for credit.

MBB 445 - Advanced Microbial Pathogenesis (3)

Recent advances in microbial pathogenesis with an emphasis on primary literature. Prerequisite: MBB 328 and either MBB 326 or HSCI 326, all with a minimum grade of C.

MBB 478 - Seminar in Molecular Epidemiology of Infectious Diseases (3)

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. Prerequisite: HSCI 326 or MBB 326 or MBB 331, with a minimum grade of C, or HSCI 338 with a minimum grade of C-. Students with credit for HSCI 478 may not take this course for further credit.

and a minimum of four courses chosen from the following list, two of which must be MBB courses. There is no upper limit on the number of courses that can be completed from this list but students will only receive credit for each course once.

BISC 303 - Microbiology (4)

A broad introduction to micro-organisms (bacteria, viruses and archaea) with an emphasis on their molecular biology, metabolism, physiology, and interactions with their hosts and environment. Labs introduce students to modern microbial techniques. Prerequisite: BISC 102, MBB 222, and MBB 231, all with a minimum grade of C-.

Section Instructor Day/Time Location
D100 Julian Guttman
May 6 – Aug 2, 2024: Tue, Thu, 9:30–10:20 a.m.
Burnaby
LAB1 Peter Hollmann
May 6 – Aug 2, 2024: Tue, Thu, 10:30 a.m.–12:20 p.m.
Burnaby
LAB2 Peter Hollmann
May 6 – Aug 2, 2024: Tue, Thu, 1:30–3:20 p.m.
Burnaby
LAB3 Peter Hollmann
May 6 – Aug 2, 2024: Tue, Thu, 3:30–5:20 p.m.
Burnaby
HSCI 338 - Virology (3)

Virology in the context of viral diseases in humans and animals. Viruses, their structures, transmission and replication in human and animal hosts, interactions with hosts and viral diseases. Prerequisite: MBB 222 with a minimum grade of C- or permission of the instructor. Corequisite: BISC 303.

HSCI 441 - Virology Laboratory (4)

Study, in a laboratory environment, of animal viruses as infectious agents that threaten human health as well as their use as biomedical tools. Includes cell culture methods, virus amplification, titration, purification, and identification, etc. Prerequisite: HSCI 338 and one of: BISC 303, BISC 357, MBB 308, or MBB 309, all with a minimum grade of C-.

HSCI 442 - Immunology Laboratory (4)

Laboratory methods in immunology. Focus on the vertebrate immune system and the molecular and cellular principles underlying immune recognition. Experimental methods designed to combine serology, biochemistry, molecular biology, cell biology and genetics as a basis for understanding immunological aspects of health and disease. Prerequisite: HSCI 326 or MBB 326, and one of BISC 303, BISC 357, MBB 308, or MBB 309W, all with a minimum grade of C-.

HSCI 477 - Seminar in Vaccine Immunology (3)

Immunological concepts of vaccines and vaccinology including vaccination, correlates of immune protection, humoral and mucosal immunity, adjuvants, recombinant vaccine technology, 'designer' vaccines, and HIV/AIDS vaccine design as a paradigm for modern vaccinology. Prerequisite: HSCI 326 or MBB 326 or HSCI 338, with a minimum grade or C- or permission of the instructor.

HSCI 482 - Senior Seminar in Infectious Diseases (3)

An in-depth overview of newly emerging and re-emerging infectious diseases in the context of disease prevention, surveillance and control. Prerequisite: HSCI 326 or MBB 326 or HSCI 338, with a minimum grade of C-.

MBB 402 - Cell Signalling in Development and Disease (3)

A mechanistic study of signal transduction pathways, their roles in development and disease with an emphasis on current literature. Prerequisite: MBB 322 or BISC 302W or BISC 333, with a minimum grade of C.

MBB 422 - Biomembranes (3)

A review of recent research on the structure, dynamics, function and biosynthesis of membranes, membrane lipids and proteins. Prerequisite: MBB 322 and MBB 309W with a minimum grade of C, MBB 324 as a pre or co-requisite.

MBB 423 - Protein Structure and Function (3)

Mechanistic principles for how protein molecules achieve diverse functions such as chemical catalysis and conformational switching. Students will learn to critique hypotheses about structural mechanisms, and to interpret the primary literature reporting on structural evidence from X-ray diffraction and spectroscopy. Prerequisite: MBB 323 or MBB 324, with a minimum grade of C.

MBB 427 - Immune Responses in Health and Disease (3)

Defects in the immunologic response to bacterial, viral and parasitic infections. The mechanisms of action of vaccines. The causes of immune-mediated diseases, such as autoimmune diseases, hypersensitivity reactions (including asthma and allergy) and organ transplant rejection. The reaction of the immune system to cancer and immunotherapy for cancer. Prerequisite: One of MBB 326, HSCI 326, MBB 426 or HSCI 426, with a minimum grade of C, or permission of the instructor. Students with credit for HSCI 427 cannot take MBB 427 for credit.

MBB 430 - Mechanisms of Secretory Transport (3)

Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells; processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of vesicle transport and membrane fusion; role in signal transduction and disease. Prerequisite: MBB 322 and MBB 331, with a minimum grade of C.

MBB 432 - Advanced Molecular Biology Techniques (4)

Laboratory with accompanying lectures designed to give practical experience in advanced contemporary molecular biology techniques. Projects will involve recombinant gene and protein manipulations to investigate the dynamics of proteins within living cells. Prerequisite: MBB 308 and MBB 331, all with a minimum grade of C, or permission of instructor. Recommended: MBB 309W.

Section Instructor Day/Time Location
D100 Chris Beh
May 6 – Aug 2, 2024: Wed, 1:30–5:20 p.m.
Burnaby
MBB 438 - Human Molecular Genetics (3)

Recent advances in human molecular genetics including genome analysis, gene therapy, genetic testing, and studies of genetic disorders. Prerequisite: MBB 331, with a minimum grade of C.

MBB 441 - Bioinformatics (3)

Examining the use of, and theory behind, bioinformatic software and algorithms for the analysis of macromolecular data. Includes consideration of recent literature and discussion of ethics in method development and analysis. Prerequisite: MBB 243 or 3 units of CMPT or equivalent with a minimum grade of C, or permission of the instructor; MBB 331 and MBB 342, with a minimum grade of C.

MBB 445 - Advanced Microbial Pathogenesis (3)

Recent advances in microbial pathogenesis with an emphasis on primary literature. Prerequisite: MBB 328 and either MBB 326 or HSCI 326, all with a minimum grade of C.

MBB 446 - The Molecular Biology of Cancer (3)

An examination of the molecular mechanisms that contribute to tumor formation, the hallmarks of cancer and their relationship to therapeutic strategies. Prerequisite: MBB 322 and 331, with a minimum grade of C, or permission of the instructor.

MBB 447 - Stem Cells - Current Trends (3)

Foundational biology of stem cell populations, technological advances, current and potential therapeutic applications. Prerequisite: MBB 322 or BISC 333, with a minimum grade of C. Students with credit for BISC 447 may not take this course for further credit. Students with credit for MBB 440 or BISC 472 under the title "Stem Cell Biology and Applications" may not take this course for further credit.

MBB 461 - Comparative Genomics (3)

Examination of the fundamentals of comparative genomics, identification and activity of functional elements in genomes, inter- and intra-species comparisons, relationship of genomic to phenotypic variation, and personalized genomics are among the topics to be explored. Comparison of genome data has impacts on medicine and many other fields of the life sciences. Prerequisite: MBB 331 and MBB 342, with a minimum grade of C. Students who have completed MBB 440 Comparative Genomics may not complete this course for further credit.

MBB 462 - Human Genomics (3)

The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues. Prerequisite: MBB 331 and MBB 342, with a minimum grade of C. Students with credit for MBB 440 with this same course title may not complete this course for further credit.

Section Instructor Day/Time Location
D100 Sophie Sneddon
May 6 – Aug 2, 2024: Tue, Thu, 8:30–10:20 a.m.
Burnaby
MBB 478 - Seminar in Molecular Epidemiology of Infectious Diseases (3)

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. Prerequisite: HSCI 326 or MBB 326 or MBB 331, with a minimum grade of C, or HSCI 338 with a minimum grade of C-. Students with credit for HSCI 478 may not take this course for further credit.

Co-operative Education Recommendation

Students are encouraged to enroll in co-operative education.

University Degree Requirements

Students must also satisfy University degree requirements for degree completion.

Writing, Quantitative, and Breadth Requirements

Students admitted to Simon Fraser University beginning in the fall 2006 term must meet writing, quantitative and breadth requirements as part of any degree program they may undertake. See Writing, Quantitative, and Breadth Requirements for university-wide information.

WQB Graduation Requirements

A grade of C- or better is required to earn W, Q or B credit

Requirement

Units

Notes
W - Writing

6

Must include at least one upper division course, taken at Simon Fraser University within the student's major subject; two courses (minimum three units each)

Q - Quantitative

6

Q courses may be lower or upper division; two courses (minimum three units each)
B - Breadth

18

Designated Breadth

Must be outside the student's major subject, and may be lower or upper division:

Two courses (minimum three units each) Social Sciences: B-Soc
Two courses (minimum three units each) Humanities: B-Hum
Two courses (minimum three units each) Sciences: B-Sci

6

Additional Breadth

Two courses (minimum three units each) outside the student's major subject (may or may not be B-designated courses, and will likely help fulfil individual degree program requirements).

Students choosing to complete a joint major, joint honours, double major, two extended minors, an extended minor and a minor, or two minors may satisfy the breadth requirements (designated or not designated) with courses completed in either one or both program areas.

Residency Requirements and Transfer Credit

The University's residency requirement stipulates that, in most cases, total transfer and course challenge credit may not exceed 60 units, and may not include more than 15 units as upper division work.

  • At least half of the program's total units must be earned through Simon Fraser University study
  • At least two thirds of the program's total upper division units must be earned through Simon Fraser University study
  • At least two thirds of the upper division units in the courses of a school offering (or joint offer) must be earned through that school at Simon Fraser University
  • For information regarding transfer, consult an Advisor.

Elective Courses

In addition to the courses listed above, students should consult an academic advisor to plan the remaining required elective courses.

Research and Directed Reading Courses

For degree credit, students are limited to nine undergraduate research and/or directed reading units. These include

MBB 471 - Undergraduate Colloquium (1)

Recent research articles on the molecular mechanisms underlying cellular activities, genomics and bioinformatics or the structure, function and interactions of macromolecules will be presented and discussed by students and faculty. This course will be available for MBB undergraduates to take once for undergraduate credit and will be offered in conjunction with MBB 821 (Cell and Molecular Biology), 841 (Genomics and Bioinformatics) or 861 Biomolecular Structure and Function. Prerequisite: Permission of the instructor.

Section Instructor Day/Time Location
D100 Edgar Young
TBD
MBB 490 - Directed Readings in Molecular Biology and Biochemistry (2)

Directed reading in a topic of molecular biology or biochemistry chosen in consultation with a supervisor. Before seeking approval for enrollment in this course, the student should have already obtained the agreement of a faculty member that he/she is willing to supervise the project, and have prepared a written proposal (of approximately one page) stating the nature of the directed reading topic. The course will include the preparation of a written term paper on the topic chosen. Prerequisite: MBB 231, with a minimum grade of C, and permission of the molecular biology and biochemistry department. Usually, upper level standing with at least 60 units in a Biochemistry major, minor or honours program will be required.

Section Instructor Day/Time Location
D100 TBD
D200 TBD
D300 TBD
D400 TBD
D500 TBD
MBB 491 - Directed Research I (5)

MBB 491 is offered as a stand-alone Directed Research course open to MBB Majors, or as the first of two courses taken consecutively to fulfill the requirements of the MBB Honours program (Option B). This course provides students with the opportunity to carry out part time laboratory research in an area of molecular biology or biochemistry under the supervision of an MBB faculty member or associate. MBB 491 coursework includes preparation of a research proposal and a report and oral presentation on the results of the project. Prerequisite: MBB 308 or MBB 309W and permission of the MBB department. Upper level standing in an MBB major, minor or honours program is required.

Section Instructor Day/Time Location
D100 TBD
D200 TBD
D300 TBD
D400 TBD
D500 TBD
D600 TBD
D700 TBD
D800 TBD
MBB 498 - Directed Research (3)

Part time laboratory research in an area of molecular biology or biochemistry under the supervision of an MBB faculty member or associate. MBB 498 coursework includes preparation of a research proposal, a report and an oral presentation on the results of the project. Prerequisite: MBB 308 or 309W; Students may not take MBB 498 concurrently with MBB 481, 482, 483, 491 or 492 or BISC 490, 491, 492W, 498 or 499.

Section Instructor Day/Time Location
D001 TBD
D002 TBD
D003 TBD
D004 TBD
D005 TBD

and corresponding courses offered by other departments (e.g. BISC 490, 491, 492, 498, 499). If students complete more than nine units of these courses, they may not apply the extra units toward the degree total (120 units).