Fall 2015 - MBB 726 G100

The Immune System I: Basis of Innate and Adaptive Immunity (4)

Class Number: 8457

Delivery Method: In Person


  • Course Times + Location:

    Sep 8 – Dec 7, 2015: Mon, Fri, 2:30–3:20 p.m.

    Sep 8 – Dec 7, 2015: Wed, 2:30–4:20 p.m.

  • Exam Times + Location:

    Dec 12, 2015
    Sat, 12:00–3:00 p.m.

  • Prerequisites:

    MBB 331 or permission of the instructor.



The basic organization of the immune system, including structure, function and genetics of antibodies, T-cell receptors, innate immune receptors, and the complement system. Innate, antibody and cellular immune responses and their control, and development of the cells involved in these responses. Students with credit for MBB or HSCI 426, MBB 826 or HSCI 726 may not complete MBB 726 for credit.


         Week   Chapter/Lecture Topic

    1. Basic Concepts in Immunology
    2. Innate Immunity: The First Lines of Defense
    3. The Induced Responses of Innate Immunity
    4. Antigen Recognition by B-cell and T-Cell Receptors
    5. The Generation of Lymphocyte Antigen Receptors
    6. Antigen Presentation to T Lymphocytes
    7. Signaling through Immune System Receptors
    8. The Development and Survival of Lymphocytes I
    9. The Development and Survival of Lymphocytes II
    10. T-cell Mediated Immunity
    11. The Humoral Immune Response
    12. Dynamics of Adaptive Immunity
    13. The Mucosal Immune System


  • 7 bi-weekly, non-cumulative exams
  • 30-min. in-class presentation
  • 3-4 page critique and summary
  • final exam will not be cumulative


A team-based learning approach will be used to cover chapter 8 (Lectures 15-18).



Abul K. Abbas et al.  Cellular and Molecular Immunology, 8th Ed. 2015. Elsevier. 
ISBN: 978-0-323-22275-4

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html