Summer 2020 - MBB 402 D100

Developmental Biology of Cell Signalling (3)

Class Number: 2601

Delivery Method: In Person


  • Course Times + Location:

    May 11 – Aug 10, 2020: Wed, Fri, 10:30 a.m.–12:20 p.m.

  • Prerequisites:

    MBB 331 or BISC 302W with a minimum grade of C.



Aspects of developmental biology in the context of signal transduction pathways. The diverse mechanisms used in cell signalling and how the various approaches to the study of signal transduction in organismal development complement each other will be examined with an emphasis on current literature.


In this lecture/seminar course, we will examine select aspects of developmental and cellular biology with a focus on signal transduction. Signaling pathways control a wide range of cellular processes and the characterization of these pathways is having a major impact on cell biology, developmental biology and medicine. In this course, we shall be examining the current literature in this rapidly developing field. We will look at how a combination of biochemistry, cell biology and genetics is being used to investigate the diverse mechanisms used in cell signaling, and examine how the various approaches to studying signal transduction compliment each other.

Specific Topics will include:

  1. Introduction: mechanisms of signal transduction, approaches available for studying signal transduction
  2. Signaling pathways involving small GTPase and trimeric G proteins
  3. Signaling by proteolytic cleavages
  4. Wnt and Hedgehog signaling pathways
  5. Regulation of signaling by Kinases and Phosphatases
  6. Other topics as time permits


  • Midterm Exam 20%
  • Oral Presentation 25%
  • Class Participation 15%
  • Final Term Paper 40%

Department Undergraduate Notes:

  • For help with writing, learning and study strategies please contact the Student Learning Commons at
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:

Registrar Notes:


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Please note that all teaching at SFU in summer term 2020 will be conducted through remote methods. Enrollment in this course acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning ( or 778-782-3112) as soon as possible to ensure that they are eligible and that approved accommodations and services are implemented in a timely fashion.