Fall 2021 - CHEM 455 D100
Synthetic Organic Chemistry (3)
Class Number: 2482
Delivery Method: In Person
Course Times + Location:
Tu, Th 8:30 AM – 10:20 AM
WMC 3511, Burnaby
Exam Times + Location:
Dec 20, 2021
7:00 PM – 10:00 PM
AQ 5019, Burnaby
Prerequisites:CHEM 381 with a minimum grade of C-, or permission of the instructor.
This course teaches the principles involved in the planning and execution of the synthesis of organic molecules. Emphasis is on synthesis of naturally occurring compounds of biological importance. Quantitative.
Please note, this course outline was accurate at the time of publication but is subject to change.
Mode of Instruction:
3 lecture hours/week; 1 tutorial hour/week
Lecture: In-Person, Burnaby Campus
Tutorial: In-Person, Burnaby Campus
An advanced treatment of the strategies and tactics that are used in multi-step organic synthesis will be provided (retrosynthetic analysis, protecting groups, linear and convergent synthesis). The principles and uses of modern synthetic methods will be introduced. The approach employed in this course will be to examine the syntheses of biologically active natural products (steroids, terpenes, alkaloids, and polyethers). This will provide a historical perspective of the development of the art and science of total synthesis over the course of the past century. This approach will also illustrate the use of functional group interconversions, carbon-carbon bond formation reactions, organometallic chemistry, asymmetric synthesis, pericyclic reactions and enzymes in total synthesis.
Combined graduate course: CHEM 755 - Synthetic Organic Chemistry (3)
- Oral Presentation 20%
- Midterm Exam 20%
- Final Exam 60%
Laszlo Kurti & Barbara Czako. Strategic Applications of Named Reactions in Organic Synthesis. 1st Edition, 2005. Publisher: Academic Press.
Department Undergraduate Notes:
A grade of C- or better is required for all prerequisite courses.
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