Fall 2021 - HSCI 440 D100

Cell Pathophysiology Laboratory (4)

Class Number: 2143

Delivery Method: In Person


  • Course Times + Location:

    Tu 1:30 PM – 5:20 PM
    BLU 9650, Burnaby

  • Prerequisites:

    HSCI 321 and one of BISC 357, MBB 308, or MBB 309W, all with a minimum grade of C-.



A review of pathophysiological mechanisms of disease with an emphasis on the molecular, cellular and genetic bases of pathology. Laboratory includes cell-biology experiments, histological preparations, and microscopic examination of normal and diseased tissues.


This course will provide students with hands-on experience in techniques in molecular biology, biochemistry and cell biology to investigate mechanisms involved in cellular pathophysiology.  Topics will include cell growth, apoptosis, cell differentiaion and cell migration.


The objectives of this course are to provide students with  knowledge in research techniques that can be used to investigate topics in cell biology as it relates to biological mechanisms governing disease pathogenesis in humans.  At the end of this course students are expected to be able to discuss the basis for normal and pathological states at the molecular, cellular and tissue level. 

There will be one 4-hour laboratory class each week. Classes will include a short lecture, in-class lab experimentation and discussion.  In addition, there will be laboratory sessions that include extended lectures on the conceptual basis of the experiments and group discussions of our experimental results.  Attendance is required.  


  • Lab reports 50%
  • Tests 30%
  • Quiz 10%
  • Participation 10%



Students must bring their own lab coat to each class. 


No required textbook for this course.  A course handbook will be distributed in the first class.

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in fall 2021 will involve primarily in-person instruction, with approximately 70 to 80 per cent of classes in person/on campus, with safety plans in place.  Whether your course will be in-person or through remote methods will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the fall 2021 term.