Fall 2021 - MBB 321 D100

Intermediary Metabolism (3)

Class Number: 4070

Delivery Method: In Person


  • Course Times + Location:

    Sep 8 – Dec 7, 2021: Mon, Wed, Fri, 9:30–10:20 a.m.

  • Exam Times + Location:

    Dec 20, 2021
    Mon, 8:30–11:30 a.m.

  • Prerequisites:

    MBB 231, with a minimum grade of C.



The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.


Lecture Topics:

  1. Review of bioenergetics, reaction mechanisms
  2. Catalysis, enzyme kinetics
  3. Carbohydrates: structure, glycogen metabolism
  4. Carbohydrates: glycolysis, citric acid cycle
  5. Carbohydrates: gluconeogenesis, pentose phosphate pathway
  6. Electron transport, oxidative phosphorylation
  7. Mitochondrial transport systems, lipid structure
  8. Lipids: beta oxidation, fatty acid biosynthesis
  9. Lipids: phospholipid biosynthesis, steroid metabolism
  10. Lipids: eicosanoid metabolism, amino acid metabolism
  11. Amino acids: urea cycle, nitrogen cycle
  12. Nucleotide biosynthesis and catabolism
  13. Metabolic regulation


  • Three 45-minute Exams (54% total = 18% each) 54%
  • Two 45-minute Cumulative Exams (36% total = 18% each) held during final exam period 36%
  • One 15-minute Practice MiniQuiz and two brief Writing Skills Assignments 10%



Nelson and Cox, Lehninger Principles of Biochemistry, 8th edition, 2021. W.H. Freeman & Company.
Achieve for Lehninger Principles of Biochemistry (1-term access).
ISBN: 9781319230906

Department Undergraduate Notes:

  • For help with writing, learning and study strategies please contact the Student Learning Commons at
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in fall 2021 will involve primarily in-person instruction, with approximately 70 to 80 per cent of classes in person/on campus, with safety plans in place.  Whether your course will be in-person or through remote methods will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the fall 2021 term.