Fall 2021 - MBB 331 D100

Molecular Biology (4)

Class Number: 4082

Delivery Method: Remote

Overview

  • Course Times + Location:

    Tu, Th 10:30 AM – 12:20 PM
    REMOTE LEARNING, Burnaby

  • Prerequisites:

    MBB 231, and BISC 202, with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction.

COURSE DETAILS:

Molecular biology is a revolution that has transformed the life sciences over the last half century and continues to advance rapidly, bringing with it profound implications for the future of biology, medicine, and agriculture. Our look at molecular biology will extend from the early history and basic principles through to recent developments and future directions. In our consideration of the current status of molecular biology, the emphasis will be placed on examining recent papers in primary scientific journals. Textbooks can only supply information that is current up to several years ago, and we must consider the primary literature to learn about recent advances. Studying the primary literature is also the best way to understand how research in molecular biology is carried out and how the science moves forward. The tutorial project is designed to familiarize you with reading and evaluating a research paper. You will choose a recent paper from any area of modern molecular biology and do a short oral presentation together with a one page summary of the paper. Oral presentations will be followed by a short question and discussion period.

Lecture Topics:

  • Introduction: Overview of molecular biology and its history
  • Structure and function of nucleic acids
  • Recombinant DNA methods
  • Replication, recombination and repair
  • Prokaryotic gene organization, expression and regulation
  • Bacterial viruses
  • Eukaryotic gene organization, expression and regulation
  • Special topics - to be arranged, but may include functional and personal genomics

Grading

  • 4 midterms (15% each) 60%
  • Online weekly quizzes 10%
  • Tutorial problems 5%
  • Presentations in tutorials 25%

NOTES:

  • Lecture: asynchronous (pre-recorded, available online)
  • Tutorial: synchronous (students are expected to attend scheduled tutorials remotely)
  • Exams: synchronous (during scheduled class time)
  • Final Exam: synchronous (held during scheduled class time)

Materials

MATERIALS + SUPPLIES:

  • Access to high-speed internet
  • Computer, webcam encouraged for tutorials

REQUIRED READING:

Molecular Biology: Principles and Practice, 2nd edition, by Michael M. Cox, Jennifer A. Doudna, Michael O'Donnell, W.H. Freeman & Company, 2015.  eText also available.
ISBN: 9781464126147

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

TEACHING AT SFU IN FALL 2021

Teaching at SFU in fall 2021 will involve primarily in-person instruction, with approximately 70 to 80 per cent of classes in person/on campus, with safety plans in place.  Whether your course will be in-person or through remote methods will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the fall 2021 term.