Summer 2021 - MBB 429 D100

RNA-mediated Gene Regulation (3)

Class Number: 2646

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 12 – Aug 9, 2021: Wed, Fri, 8:30–10:20 a.m.
    Burnaby

  • Prerequisites:

    MBB 331 with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes.

COURSE DETAILS:

Lecture topics will include, but are not limited to:

  1. RNA interference in plants and animals
  2. CRISPR bacterial antiviral defense
  3. Transcriptional and translational regulation - riboswitches, tmRNA, IRES elements, 6S RNA, etc.
  4. Post-transcriptional processing - editing, capping and splicing. Naturally occuring ribozymes.

Grading

  • Class Essay 30%
  • Short Quizzes 40%
  • Class Participation 30%

NOTES:

  • Lecture: synchronous (students are expected to attend scheduled lectures remotely with their webcam turned on)
  • Assessments: synchronous midterm exams (students must take exams during scheduled class time)
  • Final Exam: no final exam
  • Remote invigilation: Yes

REQUIREMENTS:

  • access to high-speed internet
  • computer with webcam
  • Zoom capability

Materials

REQUIRED READING:

None. This course is based on primary literature (journal articles).
Supplementary material will be made available from selected texts or journal articles.

RECOMMENDED READING:

Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000.  University Science Books. 
ISBN: 9780935702491

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

TEACHING AT SFU IN SUMMER 2021

Teaching at SFU in summer 2021 will be conducted primarily through remote methods, but we will continue to have in-person experiential activities for a selection of courses.  Such course components will be clearly identified at registration, as will course components that will be “live” (synchronous) vs. at your own pace (asynchronous). Enrollment acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes. To ensure you can access all course materials, we recommend you have access to a computer with a microphone and camera, and the internet. In some cases your instructor may use Zoom or other means requiring a camera and microphone to invigilate exams. If proctoring software will be used, this will be confirmed in the first week of class.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112).