Spring 2022 - BISC 302W D100
Genetic Analysis (3)
Class Number: 1877
Delivery Method: In Person
Course Times + Location:
Tu 10:30 AM – 11:20 AM
SWH 10041, Burnaby
Th 10:30 AM – 11:20 AM
AQ 3005, Burnaby
Exam Times + Location:
Apr 21, 2022
8:30 AM – 11:30 AM
EDB 7618, Burnaby
1 778 782-5611
Prerequisites:BISC 202 with a grade of C- or better.
Discussion and manipulations of some of the organisms and techniques applicable to genetic analysis. Students are required to come into the lab on average of two hours per week in addition to the four hour scheduled lab each week for project work. Students with credit for BISC 302 may not take this course for further credit. Writing.
Lecture/Laboratory course using model eukaryotes. We will assume you understand the basics of genes, gene mapping, recombination and segregation from Bisc 202. The laboratory will include experiments involving several model organisms, including corn, Drosophila (fruit flies), Sordaria (a filamentous fungus), and case studies involving human genetics scenarios. We are also running genotyping project using dog DNA. The work in most of the labs will be done in groups of 3 to 5. Some will be done individually also.
The project may require some time in the lab outside of regular lab times. This time is to be shared among the team members. Each semester may differ slightly.
Experiments will include gene mapping, using standard genetic crosses, as well as tetrad analysis. Other labs will cover extraction of DNA, and PCR amplification of selected DNA regions. Most labs will involve problem solving and case studies.
The lecture topics will include a review of standard genetic mapping, advanced mapping and tetrad analysis, mechanisms of recombination, gene conversion, epigenetics, transposable elements, sex-linkage (possibly including the origin and evolution of sex chromosomes), and forward and reverse genetic approaches. The final lecture(s) may cover student-selected topics. Basic lectures recorded in advance, come to class prepared to answer questions and solve problems.
This is a writing intensive course, which means that 50% of the grade will be based on written work, both formal writing and in-lab writing.
- • Laboratory Worksheets and In-Lab Writing 20%
- • Research Proposal for Genetic Screen 10%
- • Short Lab Report, Fly Eye Colour 15%
- • Dog Genotyping Report 20%
- • Weekly Canvas Quizzes 10%
- • Midterm Exam 10%
- • Final Exam 15%
This grading scheme is subject to change.
Mode of teaching:
Lecture: synchronous, in person
Laboratory: synchronous, in person
Midterm(s): synchronous; date: TBA
Final exam: synchronous; date: TBA
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TEACHING AT SFU IN SPRING 2022
Teaching at SFU in spring 2022 will involve primarily in-person instruction, with safety plans in place. Some courses will still be offered through remote methods, and if so, this will be clearly identified in the schedule of classes. You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).
Enrolling in a course acknowledges that you are able to attend in whatever format is required. You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.
Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (firstname.lastname@example.org or 778-782-3112) as early as possible in order to prepare for the spring 2022 term.