Spring 2022 - HSCI 321 D100

Human Pathophysiology (3)

Class Number: 5787

Delivery Method: In Person


  • Course Times + Location:

    Jan 10 – Apr 11, 2022: Mon, Wed, Fri, 8:30–9:20 a.m.

  • Exam Times + Location:

    Apr 21, 2022
    Thu, 7:00–10:00 p.m.

  • Prerequisites:

    MBB 231 with a minimum grade of C- or permission of the instructor.



Molecular, cellular and systemic approach to examine topics in human pathophysiology.


This course will provide an introduction to topics in the pathophysiological mechanisms of disease. In order to provide a foundation to explore human pathophysiology, this course will transfer topics of cellular and molecular biology to understand human physiology at the systemic level. Functional human anatomy will be described when necessary to understand essential concepts. This course is designed to prepare undergraduates who have an interest in medicine and human health services to pursue careers in these disciplines. In addition, this course will support the Bachelor of Science in the Faculty of Health Sciences and may be of interest to students in others faculties including Science (BISC, BPK, MBB).
Each section/topic of the course will include an examination of the molecular and cellular biology involved and provide specific examples of human disorders detailing how these processes are implicated in the pathophysiology of disease. Selected systems: · Cardiovascular system ·  Respiratory system ·  Gastrointestinal system ·  Renal system ·  Nervous system · Endocrine system. This edition of the course will also include the pathophysiology of COVID-19.


Upon the completion of this course students should be familiar with fundamental principles of human physiology and to be able to explain several biological mechanisms governing disease pathogenesis in humans.
At the end of this course, the students should have a basic overview of human physiology and be able to demonstrate and exemplify differences arising from disease states, including skills in diagnosing case studies and recognizing disease risk factors and outcomes.
In addition, this course should leave the students with the appropriate understanding and background to proceed to more intensive and comprehensive courses in the Life Sciences.


  • Midterm Exam 1 20%
  • Midterm Exam 2 20%
  • Final Exam 20%
  • Questions and Answers - TopHat/Practice Quizzes 10%
  • Case Studies 30%


Lectures are pre-recorded and available for asynchronous learning.  Scheduled class time will be used for synchronous learning that will be supported by questions, answers, and discussion period. In addition, the exams and case studies will be conducted live and require in person and live attendance at some of the scheduled class times.



Tophat subscription: https://tophat.com/


Guyton and Hall. Textbook of Medical Physiology. 11th or 12th Ed. Elsevier
ISBN: 978-1-4160-4574-8

Robbins & Cotran. Pathologic Basis of Disease. 7th or 8th Ed.

ISBN: 978-1-4160-3121-5

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in spring 2022 will involve primarily in-person instruction, with safety plans in place.  Some courses will still be offered through remote methods, and if so, this will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the spring 2022 term.