Summer 2024 - MBB 729 G100

RNA-mediated Gene Regulation (3)

Class Number: 4162

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 6 – Aug 2, 2024: Wed, Fri, 8:30–10:20 a.m.
    Burnaby

  • Exam Times + Location:

    Aug 11, 2024
    Sun, 12:00–3:00 p.m.
    Burnaby

Description

CALENDAR DESCRIPTION:

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes. Students who have taken MBB 420 or MBB 829 under the same title cannot take this course for further credit.

COURSE DETAILS:

Topics

1.  RNA interference in plants and animals.
2.  CRISPR bacterial antiviral defense.
3.  Transcriptional and translational regulation – riboswitches, tmRNA, IRES elements, 6S RNA, etc.
4.  Post-transcriptional processing – editing, capping and splicing. Naturally occurring ribozymes.

Grading

  • Essay 50%
  • Class participation 25%
  • Presentation to undergraduates 25%

Materials

REQUIRED READING:

None.  This course is based on primary literature (journal articles). Supplementary material will be made available from selected texts or journal articles.

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html

RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.