Summer 2020 - MBB 702 G100

Developmental Biology of Cell Signalling (3)

Class Number: 2780

Delivery Method: In Person


  • Course Times + Location:

    May 11 – Aug 10, 2020: Wed, Fri, 10:30 a.m.–12:20 p.m.



Aspects of developmental and cellular biology in the context of signal transduction pathways. The diverse mechanisms used in cell signalling and how the various approaches to the study of signal transduction in organismal development complement each other will be examined with an emphasis on current literature.


In this lecture/seminar course, we will examine select aspects of developmental and cellular biology with a focus on signal transduction.  Signaling pathways control a wide range of cellular processes and the characterization of these pathways is having a major impact on cell biology, developmental biology and medicine.  In this course, we shall be examining the current literature in this rapidly developing field.  We will look at how a combination of biochemistry, cell biology and genetics is being used to investigate the diverse mechanisms used in cell signaling, and examine how the various approaches to studying signal transduction compliment each other.

Specific Topics will include:

1.      Introduction: mechanisms of signal transduction, approaches available for studying signal transduction
2.      Signaling pathways involving small GTPase and trimeric G proteins
3.      Signaling by proteolytic cleavages
4.      Wnt and Hedgehog signaling pathways
5.      Regulation of signaling by Kinases and Phosphatases
6.      Other topics as time permits­


  • Two oral presentations 45%
  • Class participation 15%
  • Term paper 40%


We will read review articles and primary research papers only.  A basic development textbook may be used by students as a refresher on certain topics.  

Students who have taken MBB 437 or MBB 737 may not enroll in this course.

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:


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Please note that all teaching at SFU in summer term 2020 will be conducted through remote methods. Enrollment in this course acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning ( or 778-782-3112) as soon as possible to ensure that they are eligible and that approved accommodations and services are implemented in a timely fashion.