Spring 2022 - MBB 738 G100

Human Molecular Genetics (3)

Class Number: 2661

Delivery Method: In Person


  • Course Times + Location:

    Jan 10 – Apr 11, 2022: Tue, 10:30 a.m.–12:20 p.m.

    Jan 10 – Apr 11, 2022: Thu, 10:30 a.m.–12:20 p.m.

  • Exam Times + Location:

    Apr 22, 2022
    Fri, 12:00–3:00 p.m.

  • Prerequisites:

    MBB 331 (or BISC 331) or equivalent.



The course will consider recent advances in human molecular genetics. Topics will include genome analysis, genetic testing, and studies of genetic disorders.


This course will focus on recent advances in human molecular genetics.  This lecture and seminar course will cover the topics listed below and will integrate primary research papers into the topics. 4 lecture hours/week.

Lecture Topics:
1. Human genetic disease inheritance
2. Molecular analysis of single gene disorders
3. Genetic analysis of complex disease
4. Gene therapy
5. Gene testing
6. Cloning and stem cells
7. Animal models of human diseases
8. Ethical considerations of human genetics
9. Genetically modified organisms and food


  • Three non-cumulative exams (25% each) 75%
  • Short science communication paper 10%
  • In-class presentation 15%



Human Molecular Genetics by Strachan and Read, and Genetics and Genomics in Medicine by Strachan et al. are excellent recommended references for the material. We will also be reading papers from the primary literature.

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in spring 2022 will involve primarily in-person instruction, with safety plans in place.  Some courses will still be offered through remote methods, and if so, this will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the spring 2022 term.