We are pleased to highlight some of the exciting work that has come out of collaborations amongst C2D2 members. 

[Members, please contact if you have additional collaborations to add to this page!]


Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity

J Gen Physiol. 2021 May 3;153(5):e202012701. doi: 10.1085/jgp.202012701.

Mohammad-Reza Ghovanloo 1 2 3Koushik Choudhury # 3Tagore S Bandaru # 3Mohamed A Fouda # 1 4Kaveh Rayani # 1Radda Rusinova 5Tejas Phaterpekar 6Karen Nelkenbrecher 2Abeline R Watkins 1Damon Poburko 1Jenifer Thewalt 6Olaf S Andersen 5Lucie Delemotte 3Samuel J Goodchild 2Peter C Ruben 1

PMID: 33836525 PMCID: PMC8042605 DOI: 10.1085/jgp.202012701


2019 & Earlier

Case studies in neuroscience: a novel amino acid duplication in the NH 2-terminus of the brain sodium channel Na V 1.1 underlying Dravet syndrome

J Neurophysiol. 2019 Nov 1;122(5):1975-1980. doi: 10.1152/jn.00491.2019. Epub 2019 Sep 18.

Madeline Angus 1Colin H Peters 2Damon Poburko 1Elise Brimble 3Emily M Spelbrink 3Peter C Ruben 1

PMID: 31533007 PMCID: PMC6879963 DOI: 10.1152/jn.00491.2019