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Macromolecular Biochemistry
Research examines the structure and function of carbohydrates, proteins and nucleic acids to understand their biological roles in health and disease and to exploit them for diagnostics and therapeutics. Approaches include proteomics, x-ray crystallography, electron cryomicroscopy, computational modeling, in vitro evolution and spectroscopy.
Audas Lab
Understanding the role of noncoding RNA in the reversible formation of amyloid aggregates.
Craig Lab
The bacterial Type IV pilus apparatus is a remarkable molecular machine that rapidly assembles and disassembles protein polymers to perform diverse functions related to microbial pathogenesis.
Larijani Lab
We are interested in genome-mutating processes.
EMAIL:
MANI LARIJANI
mani_larijani@sfu.ca
Please note: All position enquiries for the Larijani Lab must be directed to larijani.lab.sfu@gmail.com
LAB ROOM:
SSB 6159
LAB PHONE:
(778) 782-6817
Setiaputra Lab
Our lab seeks to understand the molecular mechanisms underlying the mammalian DNA damage response. We are driven by our desire to better understand this fundamental aspect of our biology as well as the potential to manipulate DNA repair processes in genotoxic cancer therapy and gene editing.
Unrau Lab
The ability of RNA to recognize small substrates and promote difficult chemistry is poorly understood but is required to provide a solid foundation for the RNA world hypothesis.
Vocadlo Lab
We create new chemical and biochemical probes of glycan processing enzymes and use these to evaluate the roles of interesting glycoconjugates in cellular processes and diseases.
Young Lab
Structural and energetic principles of conformational switching in ion channels and other signaling proteins