Recent Publications

2024

Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar K
Peter Unrau, Nucleic Acids Research, Volume 52, Issue 14

Regulation of yeast polarized exocytosis by phosphoinositide lipids
Chris Beh, Cellular and Molecular Life Sciences, 81(1), art. no. 457.

C. elegans PPEF-type phosphatase (Retinal degeneration C ortholog) functions in diverse classes of cilia to regulate nematode behaviors
Michel Leroux, Scientific Reports, 14(1), art. no. 28347.

Extracellular matrix of the nervous system
Lisa Julian, Handbook of Neural Engineering: a Modern approach, Pages 97 - 1471.

Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2
David Vocadlo, npj Parkinson's Disease, 10(1), art. no. 192.

Developing a soft micropatterned substrate to enhance maturation of human induced pluripotent stem cell-derived cardiomyocytes
Glen Tibbits, Acta Biomaterialia. Volume 190, Pages 133 - 151.

Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
Amy Lee, eBioMedicine. Volume 110 105411.

High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease
David Vocadlo, Proceedings of the National Academy of Sciences of the United States of America. 121(42).

The Canadian VirusSeq Data Portal and Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology
Erin Gill, Microbial genomics. 10(10).

Snow alga Sanguina aurantia as revealed through de novo genome assembly and annotation
Lynne Quarmby, G3: Genes, Genomes, Genetics. 14(10). art. no. jkae181.

Whole-genome sequencing of Western Canadian Borrelia spp. collected from diverse tick and animal hosts reveals short-lived local genotypes interspersed with longer-lived continental genotypes
William Hsiao, Microbial genomics, 10(8).

Chromosome-scale genome assembly reveals insights into the evolution and ecology of the harmful algal bloom species Phaeocystis globosa Scherffel
Nansheng Chen, iScience, 27(8), art. no. 110575.

Whole-genome sequencing of Western Canadian Borrelia spp. collected from diverse tick and animal hosts reveals short-lived local genotypes interspersed with longer-lived continental genotypes
Nansheng Chen, Science of the Total Environment, 950, art. no. 175358.

Comparative assessment of the intragenomic variations of dinoflagellate Tripos species through single-cell sequencing
Nansheng Chen, Marine Pollution Bulletin, 206, art. no. 116690.

Pseudomonas aeruginosa in chronic lung disease: untangling the dysregulated host immune response
Amy Lee, Frontiers in Immunology, 15, art. no. 1405376.

A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies
David Vocadlo, Proceedings of the National Academy of Sciences of the United States of America, 121(27), art. no. e2314026121.

Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome
Esther Verheyen, DMM Disease Models and Mechanisms, 17(6), art. no. dmm050584.

Last but not least: emerging roles of the autophagy-related protein ATG4D
Sharon Gorski, Autophagy.