Research Labs

Bioinformatics & Genomics

Research areas include cancer genomics, personalized medicine, comparative analyses, model organism, and microbial genomics and bioinformatics. Integrated genomics, bioinformatics, and systems biology approaches are developed and used.



Cells & Disease

Molecular genetic approaches are applied to the cell and developmental biology of model systems in order to understand how cells work in health and disease. Our interests include signal transduction, cilia, morphogenesis, cell death and autophagy, cytoskeleton, gene expression, cell division and polarity. Disease targets include cancer, cardiomyopathies, ciliopathies, neurodegenerative and inflammatory diseases.

Infection & Immunity

Research focuses on understanding human viral and bacterial pathogens and how the immune system responds to these to protect the body but also in some cases to harm the body, as in transplant rejection and inflammatory diseases. Studies utilize molecular, biochemical, cell culture, and animal models.



Macromolecular Biochemistry

Research examines the structure and function of carbohydrates, proteins and nucleic acids to understand their biological roles in health and disease and to exploit them for diagnostics and therapeutics. Approaches include proteomics, x-ray crystallography, electron cryomicroscopy, computational modeling, in vitro evolution and spectroscopy.