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- Congratulations to Dr. Amy Lee: The Recipient of The Banting Research Foundation's 2022 Discovery Award
- Meet Our Newest Faculty: Dr. Dustin King on His Exploration of Weaving Western Science with Indigenous Ways of Knowing
- MBB Alumnus Profile: Meet Cory Macklin Who Overcame Challenges to Win Governor General's Silver Medal
- MBB Alumnus Profile: Meet Dr. Razvan Cojocaru, The Recipient of Governor General’s Gold Medal
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- A New Paper from Beh Lab on ER-PM membrane contact site regulation by yeast ORPs and membrane stress pathways has been published in Plos Genetics Journal
- Congratulations to Dr. Razvan Cojocaru, the recipient of Dr. Bruce Brandhorst Prizes for Best Publication and Best PhD Thesis
- Dr. Lorena Braid is featured among new and renewed Canada Research Chairs
- Learn more about Dr. King's new lab that focuses on natural ‘carbon capture’ solutions
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Mark Brockman
Professor
Health Sciences
Areas of interest
The research in our laboratory uses molecular and cell biology methods to investigate key questions at the interface of virology, pathogenesis, and the human cellular immune response to human immunodeficiency virus (HIV) infection. Ongoing studies aim to understand the impact of viral immune escape mutations on HIV protein function and cytotoxic T lymphocyte (CTL) recognition, to assess the role of HIV accessory proteins in establishment and maintenance of viral latency, and to employ new assays to identify patient-derived T cell receptors (TCR) that display enhanced ability to recognize HIV-infected cells.
Education
- B.A., Beloit College
- Ph.D., Harvard University
Selected Publications
- Ogunshola, Anmole, et al. (2018) Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV Gag escape variants. Nature Communications (Accepted)
- Alsahafi et al. (2017) Impaired downregulation of NKG2D ligands by Nef protein from elite controllers sensitize HIV-1-infected cells to ADCC. Journal of Virology 91(16):e00109-17. doi: 10.1128/JVI.00109-17
- Mwimanzi et al. (2016) Novel acylguanidine-based inhibitor of HIV-1. Journal of Virology 90(20):9495-508. doi: 10.1128/JVI.01107-16
- View more publications
Courses
Spring 2023
- HSCI 427 D100 Immune Responses in Health and Disease
- HSCI 488 D300 Directed Studies in Health Sciences
- HSCI 492 D100 Honours Research Thesis
- HSCI 493 D200 Extended Independent Research
- HSCI 494 D200 Independent Laboratory Research
- HSCI 727 G100 Immune System II: Immune Responses in Health and Disease
- MBB 427 D100 Immune Responses in Health and Disease
- MBB 490 D100 Directed Readings in Molecular Biology and Biochemistry
- MBB 491 D100 Directed Research I
- MBB 727 G100 Immune System II: Immune Responses in Health and Disease
Summer 2023
Future courses may be subject to change.