Areas of interest

Our lab uses molecular biology, protein chemistry, X-ray crystallography and other physical methods to investigate the structure and catalytic mechanism of enzymes. Currently we have many project related to viral protease self-processing, compartmentalized proteases, and eukaryotic membrane bound proteases.


  • A.A. (Theology), Golden Valley Lutheran College
  • B.Sc. (Biology), Syracuse University 
  • B.Sc. (Chemistry), University of Minnesota
  • Ph.D. (Chemistry), Ohio State University 

Selected Publications

Important Notice

MSc and PhD Student Positions Available – THE NATURE OF BIOMOLECULES

The Paetzel lab currently has openings for MSc or PhD students.
Thesis projects are designed to suit your interests and strengths and vary from chemical to computational, from pathogen to host, and from basic research to applied research.
Please visit the lab website to learn more and e-mail Dr. Paetzel ( with transcripts and CV.