- About
- People
- Faculty
- Tim Audas
- Christopher Beh
- Lorena Braid
- Fiona S.L. Brinkman
- Mark Brockman
- Jack Chen
- Jonathan Choy
- Lisa Craig
- Sharon Gorski
- Nicholas Harden
- Nancy Hawkins
- Robert Holt
- William Hsiao
- Valentin Jaumouillé
- Dustin King
- Irina Kovalyova
- Mani Larijani
- Amy Lee
- Michel Leroux
- Ryan Morin
- Ingrid Northwood
- Mark Paetzel
- Frederic Pio
- Lynne Quarmby
- Sophie Sneddon
- Jenifer Thewalt
- Glen Tibbits
- Peter Unrau
- Esther Verheyen
- Stephanie Vlachos
- David Vocadlo
- Edgar Young
- Emeritus Faculty
- Associate Members
- Adjunct Faculty
- Research Personnel
- Graduate & Postdocs
- Staff
- Department Committees
- Faculty
- Undergraduate
- Prospective Students
- Current Students
- Advising
- Courses
- Course Offerings
- Summer (1234)
- Spring (1231)
- Fall (1227)
- Summer (1224)
- Spring (1221)
- Fall (1217)
- Summer (1214)
- Spring (1211)
- Fall (1207)
- Summer (1204)
- Spring (1201)
- Fall (1197)
- Summer (1194)
- Spring (1191)
- Fall (1187)
- Summer (1184)
- Spring (1181)
- Fall (1177)
- Summer (1174)
- Spring (1171)
- Fall (1167)
- Summer (1164)
- Spring (1161)
- Fall (1157)
- Summer (1154)
- Spring (1151)
- Course Descriptions
- Course Offerings
- Degree Programs
- MBB Co-op Program
- Research Opportunities
- Scholarship & Funding
- Student Resources
- Graduate
- Prospective Students
- Current Students
- Manage Your Program
- Courses
- Course Descriptions
- Course Offerings
- Spring (1231)
- Summer (1234)
- Spring (1221)
- Summer (1224)
- Fall (1227)
- Fall (1217)
- Summer (1214)
- Spring (1211)
- Fall (1207)
- Summer (1204)
- Spring (1201)
- Fall (1197)
- Summer (1194)
- Spring (1191)
- Fall (1187)
- Summer (1184)
- Spring (1181)
- Fall (1177)
- Summer (1174)
- Spring (1171)
- Fall (1167)
- Summer (1164)
- Spring (1161)
- Fall (1157)
- Summer (1154)
- Spring (1151)
- Forms And Resources
- Events
- Graduate Student Caucus
- Research
- Research Labs
- Audas Lab
- Beh Lab
- Braid lab
- Brinkman Lab
- Brockman Lab
- Chen Lab
- Choy Lab
- Craig lab
- Gorski Lab
- Harden Lab
- Hawkins Lab
- Holt Lab
- Hsiao lab
- Jaumouillé lab
- King Lab
- Larijani Lab
- Lee Lab
- Leroux Lab
- Morin Lab
- Paetzel Lab
- Pio Lab
- Quarmby Lab
- Sen Lab
- Thewalt Lab
- Tibbits Lab
- Unrau Lab
- Verheyen Lab
- Vocadlo Lab
- Young lab
- Undergraduate Research Opportunities
- C2D2 Centre for Cell Biology, Development, and Disease
- Omics Data Science Initiative
- Research Labs
- Resources
- News & Events
- MBB Calendar
- Colloquia
- Honours & Awards
- News Archives
- 2023
- Congratulations to Dustin King, Amy Lee and David Vocadlo: recipients of New Frontiers in Research Fund
- SFU research aids fight against treatment-resistant superbugs
- Leroux lab Nature Communications paper identifies novel human disease gene linked to retinal degeneration, one of a growing number of genes associated with ciliary dysfunction (ciliopathies)
- Graduate student Minh Nguyen and his colleagues in the Craig lab reveal the mechanism of Type IV-pilus mediated bacterial secretion
- Global News BC: Dr. Fiona Brinkman Discusses How Scientists Track Mutations in the New Covid-19 Variants
- 2022
- Congratulations to Dr. Tim Audas on The Renewal of Tier 2 Canada Research Chair in Cellular Stress
- $2 Million Gift From SFU Professors Emeriti Helps Seed New Ideas at SFU Science
- Learn more about Dr. King's new lab that focuses on natural ‘carbon capture’ solutions
- Congratulations to Dr. Amy Lee: The Recipient of The Banting Research Foundation's 2022 Discovery Award
- MBB Alumnus Profile: Meet Dr. Razvan Cojocaru, The Recipient of Governor General’s Gold Medal
- MBB Alumnus Profile: Meet Cory Macklin Who Overcame Challenges to Win Governor General's Silver Medal
- Congratulations to Dr. Razvan Cojocaru, the recipient of Dr. Bruce Brandhorst Prizes for Best Publication and Best PhD Thesis
- Meet Our Newest Faculty: Dr. Dustin King on His Exploration of Weaving Western Science with Indigenous Ways of Knowing
- Congratulations to our June 2022 Graduands
- Dr. Lynne Quarmby and Her Book "WaterMelon Snow: Science, Art, and a Lone Polar Bear" is Featured in SFU Knowledge Mobilizers Series
- Congratulations to our May 2022 Graduands
- Congratulations to Dr. Mani Larijani for Being Awarded a Prestigious New Frontiers in Research Fund Grant
- A New Paper from Beh Lab on ER-PM membrane contact site regulation by yeast ORPs and membrane stress pathways has been published in Plos Genetics Journal
- Dr. Lorena Braid is featured among new and renewed Canada Research Chairs
- 2021
- 2020
- 2019
- 2018
- 2017
- 2016
- 2015
- 2023
- Support
- Faculty + Staff Portal
Brinkman Lab
Microbe-loving bioinformatics and genomics research lab, aiming to better control infectious diseases and associated immune disorders in a sustainable way.
Infectious disease control needs to be made more “sustainable”. We need to reduce selective pressure on pathogens to evolve antibiotic resistance. We need to control infectious disease outbreaks and associated immune disorders with a better understanding of the genetic, environmental and social factors that impact disease spread and severity.
The Brinkman laboratory is developing bioinformatics methods, and capitalizing on combined bioinformatics and wet-lab approaches, investigating microbes and their host/environmental interactions, to better understand key themes in infectious disease etiology, microbiome conservation, and associated immune disorders. The overall goal is to develop more sustainable, integrated approaches for disease control.
For more details, visit our research lab website.
Email:
FIONA BRINKMAN
brinkman@sfu.ca
LAB ROOM:
SSB 7165
SSB 7121
IRMACS ASB 10920
LAB PHONE:
(778) 782-4206
Selected Publications
- Almblad H, Randall TE, Liu F, Leblanc K, Groves RA, Kittichotirat W, Winsor GL, Fournier N, Au E, Groizeleau J, Rich JD, Lou Y, Granton E, Jennings LK, Singletary LA, Winstone TML, Good NM, Bumgarner RE, Hynes MF, Singh M, Stietz MS, Brinkman FSL, Kumar A, Brassinga AKC, Parsek MR, Tseng BS, Lewis IA, Yipp BG, MacCallum JL, Harrison JJ (2021). Bacterial cyclic diguanylate signaling networks sense temperature. Nature Communications 2021 Mar 31;12(1):1986.
- Lau WYV, Hoad GR, Jin V, Winsor GL, Madyan A, Gray KL, Laird MR, Lo R, Brinkman FSL (2021). PSORTdb 4.0: expanded and redesigned bacterial and archaeal protein subcellular localization database incorporating new secondary localizations. Nucleic Acids Res. 2021 Jan 8;49(D1):D803-D808.
- Maguire F*, Jia B*, Gray KL, Lau WYV, Beiko RG, Brinkman FSL (2020). Metagenome-assembled genome binning methods with short reads disproportionately fail for plasmids and genomic islands. Microb Genom. 2020 Oct 1. doi: 10.1099/mgen.0.000436. *These authors contributed equally.
- Patrick DM, Sbihi H, Dai DLY, Al Mamun A, Rasali D, Rose C, Marra F, Boutin RCT, Petersen C, Stiemsma LT, Winsor GL, Brinkman FSL, Kozyrskyj AL, Azad MB, Becker AB, Mandhane PJ, Moraes TJ, Sears MR, Subbarao P, Finlay BB, Turvey SE (2020). Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies. The Lancet Respir Med. 2020 Mar 24:S2213-2600(20)30052-7.
- McDaniel CT, Panmanee W, Winsor GL, Gill E, Bertelli C, Schurr MJ, Dongare P, Paul AT, Ko SB, Lau GW, Dasgupta N, Bogue AL, Miller WE, Mortensen JE, Haslam DB, Dexheimer P, Muruve DA, Aronow BJ, Forbes MDE, Danilczuk M, Brinkman FSL, Hancock REW, Meyer TJ, Hassett DJ (2020). AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4921-4930.
- Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen AV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran HK, Werfalli RE, Nasir JA, Oloni M, Speicher DJ, Florescu A, Singh B, Faltyn M, Hernandez- Koutoucheva A, Sharma AN, Bordeleau E, Pawlowski AC, Zubyk HL, Dooley D, Griffiths E, Maguire F, Winsor GL, Beiko RG, Brinkman FSL, Hsiao WWL, Domselaar GV, McArthur AG (2020). CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database. Nucleic Acids Res. 2020 Jan 8;48(D1):D517-D525. doi: 10.1093/nar/gkz935.
- Bertelli C, Tilley KE, Brinkman FSL (2018). Microbial genomic island discovery, visualization and analysis. Brief Bioinform. doi: 10.1093/bib/bby042.