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Infection & Immunity
Research focuses on understanding human viral and bacterial pathogens and how the immune system responds to these to protect the body but also in some cases to harm the body, as in transplant rejection and inflammatory diseases. Studies utilize molecular, biochemical, cell culture, and animal models.
Braid Lab
Our laboratory explores the identity, function, and regulation of mesenchymal stem cells (MSCs) at the interface of immunity and regeneration. We study the mechanisms used by MSCs to modulate innate and adaptive immune responses to viral and bacterial pathogens. We also investigate dysregulated MSCs as potential drivers of idiopathic and autoimmune diseases.
Brinkman Lab
Microbe-loving bioinformatics and genomics research lab, aiming to better control infectious diseases and associated immune disorders in a sustainable way.
EMAIL:
FIONA BRINKMAN
brinkman@sfu.ca
LAB ROOM:
SSB 7165
SSB 7121
IRMACS ASB 10920
LAB PHONE:
(778) 782-4206
Brockman Lab
Our research uses molecular, cell biology and single-cell transcriptomics approaches to investigate viral pathogenesis and the human cellular immune response to infection.
EMAIL:
MARK BROCKMAN
mark_brockman@sfu.ca
LAB ROOM:
TASC II 8130; BLU 9865; BLU 11750
LAB PHONE:
(778) 782-8889
Choy Lab
Research in my laboratory is focused on understanding how the immune system is activated towards transplanted organs and how it causes resultant rejection. We have provided particular attention to how innate immune signals, such as cytokines secreted by innate immune cells and vascular cells, control the activation of T cells and how the gut microbiota influences immune responses that cause organ transplant rejection. Studies are also investigating cell engineering approaches that protect blood vessels in transplanted organs and how this can be applied to prevent rejection.
Craig Lab
The bacterial Type IV pilus apparatus is a remarkable molecular machine that rapidly assembles and disassembles protein polymers to perform diverse functions related to microbial pathogenesis.
Holt Lab
The main focus in our lab (located at the BC Cancer Research Institute) is understanding and potentiating the anti-cancer immune response.
Hsiao Lab
The Centre for Infectious Disease Genomics and One Health at SFU is an interdisciplinary group of researchers interested in solving practical health problems using multidisciplinary approaches and in a One Health framework.
Jaumouillé Lab
Our laboratory use quantitative microscopy approaches to study the role of mechanical forces, cytoskeleton and membrane dynamics in the innate immune response to microbial infections and cancer.
King Lab
Our laboratory is studying the cellular mechanisms through which bacteria sense and respond to metabolites.
Larijani Lab
We are interested in genome-mutating processes.
EMAIL:
MANI LARIJANI
mani_larijani@sfu.ca
Please note: All position enquiries for the Larijani Lab must be directed to larijani.lab.sfu@gmail.com
LAB ROOM:
SSB 6159
LAB PHONE:
(778) 782-6817
Lee Lab
Systems biology of infectious diseases lab, aiming to develop mechanistic insights to the complex interface of host-pathogen interactions that can lead to impactful solutions.
