Fall 2025

Matthew Volpiana
STIM-IP3R crosstalk regulates migration of breast cancer cells.
Militsin, R., Achildiev Cohen, H., Hershfinkel, M., Levi, O., Drori, S., Yifat Raz, A., Shaked, Y., & Palty, R. (2025). The Journal of cell biology, 224(9), e202411203.
https://doi.org/10.1083/jcb.202411203

Kieran Anderson
Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers.
Turvey GL, López de Alba E, Stewart E, Cook H, Alalti A, Gawne RT, et al. Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers. J Cell Biol. 2025 Mar 11;224(5):e202409123.
https://doi.org/10.1083/jcb.202409123

Rachel Wang
Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Vittoria, M. A., Kingston, N., Kotynkova, K., Xia, E., Hong, R., Huang, L., McDonald, S., Tilston-Lunel, A., Darp, R., Campbell, J. D., Lang, D., Xu, X., Ceol, C. J., Varelas, X., & Ganem, N. J. (2022). Nature Communications, 13, 3732 (2022).
https://doi.org/10.1038/s41467-022-31399-w

Chris Tam
Heat inducible nuclear translocation of Kdm6bb drives temperature dependent sex reversal in Nile tilapia.
Lu, J., Huang, S., Wei, S., Cheng, J., Li, W., Fei, Y., ... & Chen, L. (2025). Heat inducible nuclear translocation of Kdm6bb drives temperature dependent sex reversal in Nile tilapia. PLoS genetics, 21(4), e1011664.
https://doi.org/10.1371/journal.pgen.1011664

Tong Tong Wu
Tetraspanin 4 stabilizes membrane swellings and facilitates their maturation into migrasomes.
Dharan, R., Huang, Y., Cheppali, S.K. et al. Tetraspanin 4 stabilizes membrane swellings and facilitates their maturation into migrasomes. Nat Commun 14, 1037 (2023).
https://doi.org/10.1038/s41467-023-36596-9

April Reilly
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
Santos, C. C., Schweizer, N., Cairrão, F., Ramirez, J., Osinalde, N., Yang, M., Gaspar, C. J., Rasheva, V. I., Trigo, M. L., Hensel, Z., Adrain, C., Cordeiro, T. N., Voigt, F., Gameiro, P. A., Mayor, U., & Domingos, P. M. (2025). Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling. Nature Communications, 16(1), 7523.
https://doi.org/10.1038/s41467-025-62417-2

Department of Molecular Biology and Biochemistry