featured publications

X-RAY CRYSTALLOGRAPHIC CHARACTERIZATION OF THE SARS-COV-2 MAIN PROTEASE POLYPROTEIN CLEAVAGE SITES ESSENTIAL FOR VIRAL PROCESSING AND MATURATION

Lee, J.a,b, Kenward, C.a, Worrall, L.J.a, Vuckovic, M.a, Gentile, F.c, Ton, A.T.c, Ng, M.a, Cherkasov, A.c, Strynadka, N.C.J.a, Paetzel, Mb

aDepartment of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC; bDepartment of Molecular Biology and Biochemistry, Simon Fraser University; cVancouver Prostate Centre, The University of British Columbia, Vancouver, BC

Nature Communications 13, Article number: 5196, September 2022, DOI: https://doi.org/10.1038/s41467-022-32854-4

General Variability Leads to Specific Adaptation Toward Optimal Movement Policies

Abram, S.J.a, Poggensee, K.L.b, Sánchez, N.c, ..., Donelan, J.M.d

aSchool of Engineering Science, Simon Fraser University; bDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA; cDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA; dDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University

Current Biology, Volume 32, Issue 10, 23 May 2022, pages 2222-2232.e5, https://doi.org/10.1016/j.cub.2022.04.015

Self-Assembly of PBTTT-C14 Thin Films in Supercritical Fluids

Yousefi, N.a, Pettipas, R.D.b, Kelly, T.L.b, Kaake, L.G.a

aDepartment of Chemistry, Simon Fraser University; bDepartment of Chemistry, University of Saskatchewan, Saskatoon, SK

Materials Advances, Volume 3, Issue 5, 4 February 2022, pages 2515-2523, DOI:10.1039/d1ma00847a

Sparse Functional Partial Least Squares Regression with a Locally Sparse Slope Function

Guan, T.a, Lin, Z.b, Groves, K.c, Cao, J.d

aDepartment of Mathematics and Statistics, Brock University, St. Catherines, Ontario; bDepartment of Statistics and Data Science, National University of Singapore, Singapore; cEngineered Wood Products Manufacturing, FPInnovations, Vancouver, BC; dDepartment of Statistics and Actuarial Science, Simon Fraser University

Statistics and Computing, Volume 32, Issue 2, 9 March 2022, DOI:10.1007/s11222-021-10066-y

Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome

King, D.T.a,b, Serrano-Negrón, J.E.a, Zhu, Y.a,b, Moore, C.L.c, Shoulders, M.D.c, Foster, L.J.d,e, Vocadlo, D.J.a,b

aDepartment of Molecular Biology and Biochemistry, Simon Fraser University; bDepartment of Chemistry, Simon Fraser University; cDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA; dMichael Smith Laboratories, University of British Columbia, Vancouver, BC; eDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC

Journal of the American Chemical Society, Volume 144, Issue 9, 1 March 2022, Pages 3833-3842. DOI:10.1021/jacs.1c10621

Chloroquine Treatment Induces Secretion of Autophagy-Related Proteins and Inclusion of Atg8-Family Proteins in Distinct Extracellular Vesicle Populations

Xu, J.a,b, Yang, K.C.a,b, Go, N.E.a,b, Colborne, S.a, Ho, C.J.a,b, ..., Morin, G.B.,a,c, Gorski, S.M.a,b,c,d

aCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC; bDepartment of Molecular Biology and Biochemistry, Simon Fraser University; cDepartment of Medical Genetics, University of British Columbia, Vancouver, BC; dCentre for Cell Biology, Development and Disease, Simon Fraser University

Autophagy, 28 Feb 2022, DOI:10.1080/15548627.2022.2039535

Phylogeography and Transmission of M. tuberculosis in Moldova: A Perspective Genomic Analysis

Yang, C.a,b, Sobkowiak, B.c, Naidu, V.c, ..., Colijn, C.c, Cohen, T.b

aSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, China; bDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA; cDepartment of Mathematics, Simon Fraser University

PLOS Medicine, Volume 19, Issue 2, 22 Feb 2022, Article number e1003933, DOI:10.1371/journal.pmed.1003933

Anomalous Heating in a Colloidal System

Kumar, A.a , Chétrite, R.b, Bechhoefer, J.a

aDepartment of Physics, Simon Fraser University; bLaboratoire J. A. Dieudonné, Université de Nice Sophia Antipolis, Nice, France

Proceedings of the National Academy of Sciences of the United States of America, Volume 119, Issue 5, 1 Feb 2022, e2118484119, doi: 10.1073/pnas.2118484119

 

The Natural Products Atlas 2.0: A Database of Microbially-Derived Natural Products

van Santen, J.A.a, Poynton, E.F.a, Iskakova, D.a, McMann, E.a, Alsup, T.A.b, Clark, T.N.a, Fergusson, C.H.a, Fewer, D.P.c, Hughes, A.H.d, McCadden, C.A.b, Parra, J.d, Soldatou, S.e, Rudolf, J.D.b, Janssen, E.M.-L.f, Duncan, K.R.d, Linington, R.G.a

aDepartment of Chemistry, Simon Fraser University; bDepartment of Chemistry, University of Florida, Gainesville, USA; cDepartment of Microbiology, University of Helsinki, Helsinki, Finland; dStrathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK; eMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen, UK; fDepartment of Environmental Chemistry, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Duebendorf, Switzerland

Nucleic Acids Research, Volume 50, Issue D1, 7 January 2022, Pages D1317–D1323, doi: 10.1093/nar/gkab941  

Seismic Reflections from a Lithospheric Suture Zone below the Archaean Yilgarn Craton

Calvert, A.J.a , Doublier, M.P.b,c, Sellars, S.E.a

aDepartment of Earth Sciences, Simon Fraser University; bMineral Systems Branch, Geoscience Australia; cCentre for Exploration Targeting, School of Earth and Environment, The University of Western Australia

Nature Communications, Volume 12, 13 December 2021, https://doi.org/10.1038/s41467-021-27516-w

Mouse Organ-Specific Proteins and Functions

Sun, B.a,b, Lorang, C.c, Qin, S.c, Zhang, Y.a, Liu, K.a, Li, G.c, Sun, Z.c, Francke, A.d, Utleg, A.G.c, Hu, Z.c, Wang, K.c, Moritz, R.L.c, Hood, L.c

aDepartment of Chemistry, Simon Fraser University; bDepartment of Molecular Biology and Biochemistry, Simon Fraser University; cInstitute for Systems Biology, Seattle, USA; dDepartment of Computing Science, Simon Fraser University

Cells, Volume 10, 8 December 2021, https://doi.org/10.3390/cells10123449

A Functional Proportional Hazard Cure Rate Model for Interval-Censored Data

Shi, H.a, Ma, D.b, Beg, M.F.b, Cao, J.a

aDepartment of Statistics and Acturial Science, Simon Fraser University; bSchool of Engineering, Simon Fraser University

Statistical Methods in Medical Research, Volume 31, 22 November 2021, Pages 154-168, DOI: 10.1177/09622802211052972

Processive RNA polymerization and promoter recognition in an RNA World

Cojocaru, R.a, Unrau, P.J.a

aDepartment of Molecular Biology and Biochemistry, Simon Fraser University

Science, Volume 371, 19 March 2021, Pages 1225-1232, DOI: 10.1126/science.abd9191

Half a century of global decline in oceanic sharks and rays

Pacoureau, N.a, Rigby, C.L., Kyne, P.M., Sherley, R.B., Winker, H., Carlson, J.K., Fordham, S.V., Barreto, R., Fernando, D., Francis, M.P., Jabado, R.W., Herman, K.B., Liu, K.-M., Marshall, A.D., Pollom, R.A.a, Romanov, E.V., Simpfendorfe, C.A., Yin, J.S.a, Kindsvater, H.K., Dulvy, N.K.a

aDepartment of Biological Sciences, Simon Fraser University

Nature, Volume 589, 27 January 2021, Pages 567-571, https://doi.org/10.1038/s41586-020-03173-9

PSORTdb 4.0: expanded and redesigned bacterial and archaeal protein subcellular localization database incorporating new secondary localizations

Lau, W.Y.V., Hoad, G.R., Jin, V., Winsor, G.L., Madyan, A., Gray, K.L., Laird, M.R., Lo, R., Brinkman, F.S.L.

Department of Moleculary Biology and Biochemistry, Simon Fraser University

Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D803–D808, https://doi.org/10.1093/nar/gkaa1095

Event-specific interventions to minimize COVID-19 transmission

Tupper, P.a, Boury, H.b, Yerlanov, M.a, Colijn, C.a,c

aDepartment of Mathematics, Simon Fraser University; bFaculty of Health Science, Simon Fraser University; cDepartment of Mathematics, Imperial College London, United Kingdom

Proceedings of the National Academy of Sciences of the United States of America, Volume 117, Issue 50, 15 December 2020, Pages 32038-32045 DOI: 10.1073/pnas.2019324117

Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort

Shannon, C.P., Blimkie, T.M., Ben-Othman, R., Gladish, N., Amenyogbe, N, Drissler, S, Edgar, R.D., Chan, Q., Krajden, M., Foster, L.J., Kobor, M.S., Mohn, W.W., Brinkman, R.R., Le Cao, K.-A., Scheuermann, R.H., Tebbutt, S.J., Hancock, R.E.W., Koff, W.C., Kollmann, T.R., Sadarangani, M., Lee, A.H.-Y.a

aDepartment of Molecular Biology and Biochemistry, Simon Fraser University

Frontiers in Immunology, Volume 11, 30 November 2020, Article number 578801, DOI: 10.3389/fimmu.2020.578801

Bogoliubov-Fermi Surfaces in Noncentrosymmetric Multicomponent Superconductors

Link, J.M., Herbut, I.F.

Department of Physics, Simon Fraser University

Physical Review Letters, Volume 125, Issue 23, 2 December 2020, Article number 237004, DOI:10.1103/PhysRevLett.125.237004

A single silicon colour centre resolved

Simmons, S.

Department of Physics, Simon Fraser University

Nature Electronics, Volume 3, 7 December 2020, Pages 734-735, DOI: 10.1038/s41928-020-00516-2

Conservation: Goldilocks Nations for Restoring Reef Sharks  

Dulvy, N.K., Yan, H.F.

Earth to Ocean Group, Department of Biological Sciences, Simon Fraser University

Current Biology, Volume 30, Issue 23, 7 December 2020, Pages R1415-R1418, DOI: https://doi.org/10.1016/j.cub.2020.08.060

Understanding the role of acid-base interactions using architecturally-controlled, pyridyl-bearing sulfonated phenylated polyphenylenes  

Xu, S., Wu, Y., Adamski, M., Fraser, K., Holdcroft, S.

Department of Chemistry, Simon Fraser University

Journal of Materials Chemistry A, Volume 8, Issue 45, 7 December 2020, Pages 23866-23883, DOI: 10.1039/d0ta08203a

Control of the noncollinear interlayer exchange coupling

Nunn, Z.R.a, Abert, C.b,c, Suess, D.b,c, Girt, E.a

aDepartment of Physics, Simon Fraser University; bFaculty of Physics, University of Vienna, Austria; cUniversity of Vienna Research Platform Mathematics-Magnetism-Materials, University of Vienna, Austria

Science Advances, Volume 6, Issue 48, 25 November 2020, Article number eabd8861, DOI: 10.1126/sciadv.abd8861